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  1. The management of food allergy in children requires elimination of the offending allergens, which significantly contribute to micronutrient intake. Vitamin and mineral supplementation are commonly suggested as...

    Authors: Rosan Meyer, Claire De Koker, Robert Dziubak, Ana-Kristina Skrapac, Heather Godwin, Kate Reeve, Adriana Chebar-Lozinsky and Neil Shah
    Citation: Clinical and Translational Allergy 2015 5:11
  2. Non-steroidal anti-inflammatory drugs (NSAIDs) are reported to be the second most common cause of drug hypersensitivity. In 2011, experts from the EAACI/ENDA group and GA2LEN proposed a new classification system ...

    Authors: Christoffer V Nissen, Carsten Bindslev-Jensen and Charlotte G Mortz
    Citation: Clinical and Translational Allergy 2015 5:10
  3. Molecular-based allergy diagnostics are gaining popularity in clinical practice. Our aim was to evaluate their role in the tropics, given the inherent genetic and environmental differences.

    Authors: Amelia Santosa, Anand Kumar Andiappan, Olaf Rotzschke, Hung Chew Wong, Amanda Chang, Mei Bigliardi-Qi, De-Yun Wang and Paul Lorenz Bigliardi
    Citation: Clinical and Translational Allergy 2015 5:9
  4. It is unknown whether food allergy (FA) in an unselected population is comparable to those from an outpatient clinic population.

    Authors: Thuy-My Le, Els van Hoffen, Ischa Kummeling, James Potts, Barbara K Ballmer-Weber, Carla AFM Bruijnzeel-Koomen, Ans FM Lebens, Jonas Lidholm, Titia M Lindner, Alan Mackie, EN Clare Mills, Ronald van Ree, Stefan Vieths, Montserrat Fernández-Rivas, Peter G Burney and André C Knulst
    Citation: Clinical and Translational Allergy 2015 5:8
  5. The disparity between reported and diagnosed food allergy makes robust diagnosis imperative. The allergy-focussed history is an important starting point, but published literature on its efficacy is sparse. Usi...

    Authors: Isabel J Skypala, Carina Venter, Rosan Meyer, Nicolette W deJong, Adam T Fox, Marion Groetch, J N Oude Elberink, Aline Sprikkelman, Louiza Diamandi and Berber J Vlieg-Boerstra
    Citation: Clinical and Translational Allergy 2015 5:7
  6. The editors of Clinical and Translational Allergy would like to thank all of our reviewers who have contributed to the journal in Volume 4 (2014).

    Authors: Clive Grattan
    Citation: Clinical and Translational Allergy 2015 5:6
  7. Non-hereditary angioedema (non-HAE) is characterized by local swelling due to self-limiting, subcutaneous or submucosal extravasation of fluid, and can be divided into three subtypes. These subtypes are believ...

    Authors: Karlijn J G Schulkes, Mignon T Van den Elzen, Erik C Hack, Henderikus G Otten, Carla A F M Bruijnzeel-Koomen and André C Knulst
    Citation: Clinical and Translational Allergy 2015 5:5
  8. Many food allergy guidelines have been published worldwide over recent years. The United Kingdom National Institute of Health and Clinical Excellence guidelines and The Royal College of Paediatrics and Child H...

    Authors: Liane Reeves, Rosan Meyer, Judith Holloway and Carina Venter
    Citation: Clinical and Translational Allergy 2015 5:4
  9. Allergic sensitisation to food may occur through non-gastrointestinal routes such as via skin or lung. We recently demonstrated in mice that cutaneous or respiratory pre-exposures to peanut proteins on intact ...

    Authors: Sophie Wavrin, Herve Bernard, Jean-Michel Wal and Karine Adel-Patient
    Citation: Clinical and Translational Allergy 2015 5:3
  10. Allergic rhinitis is a common problem in childhood and adolescence, with a negative impact on the quality of life of patients and their families. The treatment modalities for allergic rhinitis include allergen...

    Authors: Alexandra F Santos, Luis Miguel Borrego, Giuseppina Rotiroti, Glenis Scadding and Graham Roberts
    Citation: Clinical and Translational Allergy 2015 5:2
  11. Allergoids are chemically modified allergen extracts administered to reduce allergenicity and to maintain immunogenicity. Oralair® (the 5-grass tablet) is a sublingual native grass allergen tablet for pre- and...

    Authors: Bram G Verheggen, Kirsten Y Westerhout, Carl H Schreder and Matthias Augustin
    Citation: Clinical and Translational Allergy 2015 5:1
  12. Regulatory T (Treg) cells are implicated in the development and progression of eosinophilic granulomatosis with polyangiitis (EGPA). We previously showed beneficial effects of intravenous immunoglobulin (IVIG) th...

    Authors: Naomi Tsurikisawa, Hiroshi Saito, Chiyako Oshikata, Takahiro Tsuburai and Kazuo Akiyama
    Citation: Clinical and Translational Allergy 2014 4:38
  13. Schnitzler’s syndrome is an autoinflammatory disorder characterized by the association of a monoclonal IgM (or IgG) gammopathy, a chronic urticarial rash, and signs and symptoms of systemic inflammation, inclu...

    Authors: Heleen D de Koning
    Citation: Clinical and Translational Allergy 2014 4:41
  14. Food challenge tests are the gold standard in diagnosing food allergy. Guidelines provide scoring systems to classify symptoms during challenge and typically recommend that challenges are considered positive w...

    Authors: Francine C van Erp, André C Knulst, Yolanda Meijer, Carmelo Gabriele and Cornelis K van der Ent
    Citation: Clinical and Translational Allergy 2014 4:43
  15. Although efforts to improve the classification of hypersensitivity/allergic diseases have been made, they have not been considered a top-level category in the International Classification of Diseases (ICD)-10 ...

    Authors: Luciana Kase Tanno, Moises A Calderon, Bruce J Goldberg, Cezmi A Akdis, Nikolaos G Papadopoulos and Pascal Demoly
    Citation: Clinical and Translational Allergy 2014 4:42
  16. Allergy to wheat can present clinically in different forms: Sensitization to ingested wheat via the gastrointestinal tract can cause traditional food allergy or in combination with exercise, Wheat-Dependent Ex...

    Authors: Morten J Christensen, Esben Eller, Charlotte G Mortz and Carsten Bindslev-Jensen
    Citation: Clinical and Translational Allergy 2014 4:39
  17. A knowledgeable and competent dietitian is an integral part of the food allergy multidisciplinary team, contributing to effective diagnosis and management of food allergic disorders. Little is currently known ...

    Authors: Kate Maslin, Rosan Meyer, Liane Reeves, Heather Mackenzie, Anne Swain, Wendy Stuart-Smith, Rob Loblay, Marion Groetch and Carina Venter
    Citation: Clinical and Translational Allergy 2014 4:37
  18. Polysensitisation is common in patients with respiratory allergy in Spain. Selection of the best allergen immunotherapy (AIT) is difficult in polysensitised patients. The present study was designed to help all...

    Authors: Carmen Vidal, Ernesto Enrique, Angeles Gonzalo, Carmen Moreno and Ana I Tabar
    Citation: Clinical and Translational Allergy 2014 4:36
  19. Rebamipide eyedrops are approved in Japan for the treatment of dry eye disease. Some patients with allergic conjunctival diseases also manifest dry eye. Earlier we reported that rebamipide suppressed polyI:C-i...

    Authors: Mayumi Ueta, Jun Shoji, Chie Sotozono and Shigeru Kinoshita
    Citation: Clinical and Translational Allergy 2014 4:40
  20. The positive and negative predictive values of specific IgE to penicillins are not well established for penicillin hypersensitivity. One reason may be that serum IgE levels to penicillin diminish over time. Th...

    Authors: Janni Hjortlund, Charlotte Gotthard Mortz, Tore Bjerregaard Stage, Per Stahl Skov, Ronald Dahl and Carsten Bindslev-Jensen
    Citation: Clinical and Translational Allergy 2014 4:34
  21. Few data are available about the inflammatory cytokine profile of bronchoalveolar lavage (BAL) from young children with frequent wheeze. The first aim was to investigate the BAL cellular and cytokine profiles ...

    Authors: Kristiina Malmström, Maili Lehto, Marja-Leena Majuri, Timo Paavonen, Seppo Sarna, Anna S Pelkonen, L Pekka Malmberg, Harry Lindahl, Merja Kajosaari, Sejal Saglani, Harri Alenius and Mika J Mäkelä
    Citation: Clinical and Translational Allergy 2014 4:35
  22. Atopic dermatitis (AD) is a common inflammatory skin disorder and characterized by abnormalities in both skin barrier structures and alternations of the immune response. Molecular genetics have dramatically ch...

    Authors: Alexander Salava and Antti Lauerma
    Citation: Clinical and Translational Allergy 2014 4:33
  23. Few population-based cohort studies have examined reported food hypersensitivity longitudinally. We investigated prevalence, incidence and remission of perceived food hypersensitivity among schoolchildren from...

    Authors: Anna Winberg, Åsa Strinnholm, Linnea Hedman, Christina E West, Matthew S Perzanowski and Eva Rönmark
    Citation: Clinical and Translational Allergy 2014 4:32
  24. The cornerstone for management of Food protein-induced gastrointestinal allergy (FPGIA) is dietary exclusion; however the micronutrient intake of this population has been poorly studied. We set out to determin...

    Authors: Rosan Meyer, Claire De Koker, Robert Dziubak, Heather Godwin, Gloria Dominguez-Ortega and Neil Shah
    Citation: Clinical and Translational Allergy 2014 4:31
  25. Peanut allergy is common and can be a cause of severe, life-threatening reactions. It is rarely outgrown like other food allergies, such as egg and milk. Peanut allergy has a significant effect on the quality ...

    Authors: Katherine Anagnostou and Andrew Clark
    Citation: Clinical and Translational Allergy 2014 4:30
  26. Montelukast is an effective and well-tolerated treatment for the prophylaxis and chronic treatment of asthma, acute prevention of exercise-induced bronchoconstriction and symptomatic relief of seasonal allergi...

    Authors: Constanze Fey, Ursula Thyroff-Friesinger and Spencer Jones
    Citation: Clinical and Translational Allergy 2014 4:29
  27. The knowledge on molecular allergy diagnosis is continuously evolving. It is now time for the clinician to integrate this knowledge and use it when needed to improve the accuracy of diagnosis and thus provide ...

    Authors: Olga Luengo and Victòria Cardona
    Citation: Clinical and Translational Allergy 2014 4:28
  28. Fish is an important cause of food allergy. Studies on fish allergy are scarce and in most cases limited to serological evaluation. Our objective was to study patterns of self-reported allergy and tolerance to...

    Authors: Karlijn JG Schulkes, Rob JB Klemans, Lidy Knigge, Marjolein de Bruin-Weller, Carla AFM Bruijnzeel-Koomen, Åsa Marknell deWitt, Jonas Lidholm and André C Knulst
    Citation: Clinical and Translational Allergy 2014 4:27
  29. A previous cross-sectional survey highlighted that restaurant staff in Brighton had gaps in their knowledge of food allergy, which could lead to the provision of unsafe meals to food-allergic customers. A food...

    Authors: Samuel Bailey, Tiffany Billmeier Kindratt, Helen Smith and David Reading
    Citation: Clinical and Translational Allergy 2014 4:26
  30. Characterisation of the specific antibody response, including the epitope binding pattern, is an essential task for understanding the molecular mechanisms of food allergy. Examination of antibody formation in ...

    Authors: Jeanette Lund Madsen, Stine Kroghsbo, Charlotte Bernhard Madsen, Irina Pozdnyakova, Vibeke Barkholt and Katrine Lindholm Bøgh
    Citation: Clinical and Translational Allergy 2014 4:25
  31. The best combination of questions to define asthma in epidemiological asthma studies is not known. We summarized the operational definitions of asthma used in prevalence studies and empirically assess how asth...

    Authors: Ana Sá-Sousa, Tiago Jacinto, Luís Filipe Azevedo, Mário Morais-Almeida, Carlos Robalo-Cordeiro, António Bugalho-Almeida, Jean Bousquet and João Almeida Fonseca
    Citation: Clinical and Translational Allergy 2014 4:24
  32. SUBLIVAC FIX Birch (SUB-B) is a liquid oral preparation of Betula verrucosa pollen extract for the treatment of allergic rhinitis/rhinoconjuctivitis induced by birch pollen. The major allergen content of SUB-B an...

    Authors: Ludger Klimek, Annette Sperl, Esther van Twuijver, Ronald van Ree, Huub Kleinjans, Johan Diderik Boot and Oliver Pfaar
    Citation: Clinical and Translational Allergy 2014 4:23
  33. At present, there is no European report on clinically relevant systemic reactions due to the regular use of allergen immunotherapy (AIT), administered either subcutaneously or sublingually (SCIT and SLIT, resp...

    Authors: Moises A Calderón, Pablo Rodríguez del Río, Carmen Vidal, Jocelyne Just, Oliver Pfaar, Allan Linneberg and Pascal Demoly
    Citation: Clinical and Translational Allergy 2014 4:22
  34. Authors: Andrew Gibson, Monday Ogese, Andrew Sullivan, Eryi Wang, Katy Saide, Paul Whitaker, Daniel Peckham, Lee Faulkner, B Kevin Park and Dean J Naisbitt
    Citation: Clinical and Translational Allergy 2014 4(Suppl 3):O2

    This article is part of a Supplement: Volume 4 Supplement 3