Volume 4 Supplement 3

6th Drug Hypersensitivity Meeting (DHM 6)

Meeting abstracts

Publication of this supplement was funded by the European Academy of Allergy and Clinical Immunology (EAACI).

6th Drug Hypersensitivity Meeting (DHM 6). Go to conference site.

Bern, Switzerland9-12 April 2014

Concatenated PDF 4S3

Page 1 of 4

Mechanisms that limit proliferative potential of drug-specific LTT in drug-induced severe cutaneous adverse reaction patients

Authors: Laurence Valeyrie-Allanore, Maja Mockenhaupt, Peggy Sekula, François Berrehar, Nicolas Ortonne, Haudrey Assier, Colette Goujon, Martine Bagot, Jean-Claude Roujeau, Armand Bensussan and Sabine Le Gouvello

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):O1

Content type: Oral presentation Published on: 18 July 2014
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Negative regulation by Programmed Death Ligand-1 during drug-specific priming of T-cells and the influence of Programmed Death-1 on effector T-cell function

Authors: Andrew Gibson, Monday Ogese, Andrew Sullivan, Eryi Wang, Katy Saide, Paul Whitaker, Daniel Peckham, Lee Faulkner, B Kevin Park and Dean J Naisbitt

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):O2

Content type: Oral presentation Published on: 18 July 2014
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Identification of susceptible HLA class II co-amoxiclav genotypes based on the analysis of drug-specific T-cells from patients with liver injury

Authors: Katy Saide, Seung-Hyun Kim, Ye Yuan, Ann Daly, Ana Alfirevic, Munir Pirmohamed, Kevin Park and Dean Naisbitt

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):O3

Content type: Oral presentation Published on: 18 July 2014
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A prospective study of HLA*B-5801 genotyping in preventing allopurinol- induced severe cutaneous adverse reactions

Authors: Tai-Ming Ko, Jer-Yuarn Wu, Yuan-Tsong Chen and Chen-Yang Shen

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):O4

Content type: Oral presentation Published on: 18 July 2014
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Vancomycin-specific T Cell responses in allergic and non-allergic individuals

Authors: Marta E Polak, Carolann McGuire, Alvin Lee, Ursula Quinn, Anthony Williams, Efrem Eren and Michael R Ardern-Jones

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):O5

Content type: Oral presentation Published on: 18 July 2014
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Overlap between maculopapular exanthema and DRESS among cutaneous adverse drug reactions in a dermatology ward (2008-2012)

Authors: Miguel Pinto Gouveia, Ana Gameiro, Inês Coutinho, Neide Pereira and Margarida Gonçalo

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):O6

Content type: Oral presentation Published on: 18 July 2014
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Diagnostic usefulness of histamine release test (HRT) and skin tests in IgE-mediated allergy to clavulanic acid

Authors: Fernando Pineda, Adriana Ariza, Cristobalina Mayorga, Inmaculada Perez, Rosario Gonzalez-Mendiola, Natalia Blanca, Galicia Davila, Nieves Cabañes, Gabriela Canto, Jose Julio Laguna, Carlos Senent, Per Stahl Skov, Ricardo Palacios and Miguel Blanca

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):O7

Content type: Oral presentation Published on: 18 July 2014
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Histopathology of the exanthema in DRESS in correlation with markers of severe systemic involvement

Authors: Margarida Gonçalo, Inês Coutinho, Miguel Gouveia, Rita Cabral, Neide Pereira, José Carlos Cardoso and Óscar Tellechea

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):O8

Content type: Oral presentation Published on: 18 July 2014
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The "nocebo effect" in drug hypersensitivity diagnosis

Authors: Luisa Bommarito, Sabrina Mietta and Gianni Cadario

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):O9

Content type: Oral presentation Published on: 18 July 2014
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A new humanized in vitro model of IgE-mediated rapid desensitization

Authors: Matthieu Picard, Joana Caiado, Pedro Giavina-Bianchi and Mariana Castells

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):O10

Content type: Oral presentation Published on: 18 July 2014
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DNA copy number variations in drug reaction with eosinophilia and systemic symptoms (DRESS) identifying 2 new candidates genes

Authors: Anne-Claire Bursztejn, Christophe Nemos, Richard Redon, Philippe Trechot, Isabelle Gastin and Annick Barbaud

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):O11

Content type: Oral presentation Published on: 18 July 2014
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Cutaneous adverse drug reactions induced by Oxcarbazepine

Authors: Yi-Hsin Hsiao and Wen-Hung Chung

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):O12

Content type: Oral presentation Published on: 18 July 2014
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Nonirritant concentrations and amount of active ingredient in drug patch tests optimal concentrations for DPTs

Authors: Delphine Brajon, Sophie Menetre, Julie Waton, Claire Poreaux and Annick Barbaud

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P1

Content type: Poster presentation Published on: 18 July 2014
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HLA class I-drug-T-cell receptor interactions in SJS/TEN

Authors: Craig Rive, Rebecca Pavlos, David Ostrov, Pablo Plasencia, Shien-Iu Hung, WenHung Chung, Bjoern Peters, Soren Buus, Simon Mallal and Elizabeth Phillips

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P2

Content type: Poster presentation Published on: 18 July 2014
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An immunohistochemical study of the granulysin expression of 6 types of proven adverse cutaneous drug reaction

Authors: Marie Weinborn, Annick Barbaud, François Truchetet, Philippe Beurey, Lucie Germain, Jean-Luc Schmutz and Bernard Cribier

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P3

Content type: Poster presentation Published on: 18 July 2014
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Allergic reactions to insulin: a case report

Authors: Rita Aguiar, Natalia Fernandes, Ana Mendes and Manuel Pereira-Barbosa

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P4

Content type: Poster presentation Published on: 18 July 2014
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Severe anaphylaxis during sentinel lymph node biopsy (SLNB)

Authors: Andreia Ferrão Vasconcelos Pinela, Cintia Cruz, Elza Tomaz and Filipe Inacio

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P5

Content type: Poster presentation Published on: 18 July 2014
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Anaphylaxis to gadobutrol and gadoterate meglumine in a patient with low grade astrocytoma

Authors: Juan Manuel Escobar Montalvo, Ruth Mielgo Ballesteros and Ruth Barranco Jimenez

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P6

Content type: Poster presentation Published on: 18 July 2014
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NSAID intolerance: it is not always what it seems

Authors: Tatjana Pecaric Petkovic, Werner J Pichler and Oliver Hausmann

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P7

Content type: Poster presentation Published on: 18 July 2014
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Anaphylaxis due to I.V. prednisolone application in two patients suffering from multiple sclerosis

Authors: Tamar Kinaciyan

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P8

Content type: Poster presentation Published on: 18 July 2014
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Hypersensitivity response to the medicinal product "Zorex": clinical experience

Authors: Marina Voronova, Olga Drobik and Elena Bashvinova

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P9

Content type: Poster presentation Published on: 18 July 2014
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Treatment and outcome of toxic epidermal necrolysis in 32 Chinese patients: a hospital-based study

Authors: Ting Xiao, Li-Ming Zhang and Yan Zhao

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P10

Content type: Poster presentation Published on: 18 July 2014
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Strong association between hla-a*02:06 and acetaminophen-related stevens-johnson syndrome with severe mucosal involvements in the Japanese

Authors: Mayumi Ueta, Chie Sotozono, Hiromi Sawai, Katsushi Tokunaga and Shigeru Kinoshita

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P11

Content type: Poster presentation Published on: 18 July 2014
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C-reactive protein and procalcitonin in patients with DRESS syndrome

Authors: Anne Taegtmeyer, Alexandra Raetz Bravo, Barbara Zimmermanns, Evangelia Liakoni, Stephan Kraehenbuehl and Manuel Haschke

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P12

Content type: Poster presentation Published on: 18 July 2014
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Association between HLA-B*13:01 and DIHS/DRESS due to dapson in a Japanese patients of pityriasis lichenoides et varioliformis acuta (PLEVA)

Authors: Hideaki Watanabe, Erika Tonooka, Hirokazu Uno, Takeshi Ozeki, Taisei Mushiroda and Hirohiko Sueki

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P13

Content type: Poster presentation Published on: 18 July 2014
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A case of toxic epidermal necrolysis with extensive intestinal involvement

Authors: Keiko Nishimura, Riichiro Abe, Makiko Yamaguchi, Takamasa Ito, Shinichi Nakazato, Youhei Hamade, Nao Saito, Reine Moriuchi, Takehiko Katsurada, Mika Watanabe, Maroto Maria Iitani and Hiroshi Shimizu

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P14

Content type: Poster presentation Published on: 18 July 2014
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Effects of immunomodulating therapies on mortality in patients with severe cutaneous adverse reactions in comparison with supportive care only: a systematic review

Authors: Stefanie Zimmermann, Peggy Sekula, Moritz Venhoff, Jean Claude Roujeau, Martin Schumacher and Maja Mockenhaupt

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P15

Content type: Poster presentation Published on: 18 July 2014
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The causative drugs and the prevalence of severe bullous hypersensitivity reactions

Authors: Ekaterina Vertieva, Pavel Kolkhir and Natalia Teplyuk

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P16

Content type: Poster presentation Published on: 18 July 2014
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Allopurinol is the most common cause of DRESS syndrome in Hungarian patients

Authors: Ágnes Kinyó, Katinka Ónodi-Nagy, Erika Varga, István Balázs Németh, Irma Korom, Rolland Gyulai, Lajos Kemény and Zsuzsanna Bata-Csörgõ

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P17

Content type: Poster presentation Published on: 18 July 2014
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Clinical pattern of liver injury in drug reaction with eosinophilia and systemic symptoms (DRESS): a retrospective study in Taiwan

Authors: Kai-Lung Chen, I-Chun Lin, Hong-Chih Yang and Chia-Yu Chu

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P18

Content type: Poster presentation Published on: 18 July 2014
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A rare case of DRESS (Drug Reaction With Eosinophilia And Systemic Symptoms) with important involvement of heart, liver, central nervous system and bone marrow

Authors: Jan Schroeder, Antonella Citterio, Gloria Anversano, Ambra Mascheri, Edgardo Bonacina, Olivia Leoni, Giuseppe Scibilia, Alberto Roghi, Chiara Gamba and Elide Pastorello

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P19

Content type: Poster presentation Published on: 18 July 2014
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Differential cytokine/chemokine profiles and reactivation of human herpes viruses in various forms of cutaneous adverse drug reactions. A comparative study in Taiwan

Authors: Chia-Yu Chu, Yi-Chun Chen, Che-Wen Yang, Kai-Lung Chen, Yung-Tsu Cho, Chia-Ying Chang and I-Chun Lin

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P20

Content type: Poster presentation Published on: 18 July 2014
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The role of malignancy in the mortality of Stevens-Johnson syndrome and toxic epidermal necrolysis

Authors: Jennifer Wu, Yung-Yi Lee and Wen-Hung Chung

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P21

Content type: Poster presentation Published on: 18 July 2014
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Aspirin hypersensitivity in Iranian patients with chronic rhinosinusitis and nasal polyposis: prevalence and comorbid factors

Authors: Hossein Esmaeilzadeh, Mohammad Nabavi, Saba Arshi, Mohammad Hassan Bemanian, Ahmad Bahrami, Morteza Fallahpour, Negar Mortazavi and Nima Rezaei

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P22

Content type: Poster presentation Published on: 18 July 2014
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Evaluation of the inhibitory effect of various drugs / active ingredients on the activity of human diamine oxidase in vitro

Authors: Roland Leitner, Eva Zoernpfenning and Albert Missbichler

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P23

Content type: Poster presentation Published on: 18 July 2014
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Anaphylactic reactions induced by NSAID according to data of Vilnius University Hospital Santariskiu Klinikos

Authors: Olesia Gaidej, Gabija Didziokaite, Neringa Buterleviciute, Viktorija Paltarackiene, Gintare Nakrosyte, Ana Kozlovska, Laura Malinauskiene and Violeta Kvedariene

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P24

Content type: Poster presentation Published on: 18 July 2014
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Aspirin desensitization for urgent endovascular treatment of the aneurysm

Authors: Rita Aguiar, Natália P Fernandes, Ana Mendes, Elisa Pedro and Manuel Pereira-Barbosa

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P25

Content type: Poster presentation Published on: 18 July 2014
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Urticaria by neurogenic switching of gastroesophageal chemical-infective inflammation: a phenomenon that should always be evaluated in suspected multiple drug hypersensitivity

Authors: Fabio De Bartolomeis, Alfonso Savoia, Ernesto Aitella, Carlo Sacerdoti, Adele Parlato, Carmen Palmieri and Corrado Astarita

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P26

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The predictive value of the in vitro platelet toxicity assay (iPTA) for the diagnosis of hypersensitivity reactions to sulfonamides: a case-control study

Authors: Abdelbaset Elzagallaai, Gideon Koren and Michael Rieder

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P27

Content type: Poster presentation Published on: 18 July 2014
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T cell activation in biological diagnosis of amoxicillin delayed hypersensitivity

Authors: Luc de Chaisemartin, Suzy Lim, Catherine Neukirch, Marguerite Thetis, Pascale Nicaise-Roland, Sandy Peltier and Sylvie Chollet-Martin

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P28

Content type: Poster presentation Published on: 18 July 2014
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Dynamics of chemokines in severe drug hypersensitivity

Authors: Hideo Asada, Kohei Ogawa, Ayako Hasegawa, Fumi Miyagawa, Hideaki Watanabe, Hirohiko Sueki, Mikiko Tohyama, Koji Hashimoto, Yoko Kano, Tetsuo Shiohara, Hiroyuki Fujita and Michiko Aihara

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P29

Content type: Poster presentation Published on: 18 July 2014
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Comparison of basophil activation test and lymphocyte transformation test as diagnostic assays for drug hypersensitivity

Authors: Takeya Adachi, Hayato Takahashi, Takeru Funakoshi, Hiroyuki Hirai, Akihiko Hashiguchi, Masayuki Amagai and Keisuke Nagao

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P30

Content type: Poster presentation Published on: 18 July 2014
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Use of in vitro tests to assess the causative drugs for NSAIDs-induced type I hypersensitivity

Authors: Wan-Chun Chang, Bi-Kai Hsu, Wen-Hung Chung and Shuen-Iu Hung

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P31

Content type: Poster presentation Published on: 18 July 2014
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Inclusion of clavulanic acid determinants in the basophil activation test improves the evaluation of immediate reactions to amoxicillin-clavulanic acid

Authors: Tahia D Fernandez, Adriana Ariza, Maria Salas, Maria I Montañez, Inmaculada Doña, Lidia Melendez, Maria D Cañamero, Miguel Blanca, Maria J Torres and Cristobalina Mayorga

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P32

Content type: Poster presentation Published on: 18 July 2014
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Evaluation of immediate allergic reactions to dipyrone using dipyrone metabolites in basophil activation test

Authors: Maria Isabel Montanez, Elena Garcia-Martin, Adriana Ariza, Maria Jose Torres, Jose AG Agundez, Cristobalina Mayorga, Inmaculada Doña, Natalia Blanca-Lopez, Maria A Zambonino, Inmaculada Andreu and Miguel Blanca

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P33

Content type: Poster presentation Published on: 18 July 2014
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Basophil activation test in allergic patients to platins undergoing rapid desensitization

Authors: Pedro Giavina-Bianchi, Joana Caiado, Matthieu Picard, Violeta Régnier Galvão and Mariana Castells

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P34

Content type: Poster presentation Published on: 18 July 2014
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Predominance of IL-5-secreting drug-specific T cells in subgroups of patients with drug-induced delayed-type hypersensitivity reaction

Authors: Wolfgang Pfützner, Carolin Intrup and Christian Möbs

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P35

Content type: Poster presentation Published on: 18 July 2014
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Desensitization induces hyporesponsiveness and cell-surface phenotype changes on mouse mast cells

Authors: Pedro Giavina-Bianchi, Matthieu Picard, Joana Caiado, Veronica Mezzano and Mariana Castells

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P36

Content type: Poster presentation Published on: 18 July 2014
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Protein modification by biotinylated amoxicillin: usefulness in studies on allergy towards beta-lactams

Authors: Adriana Ariza, Daniel Collado, Yolanda Vida, María Isabel Montañez, Ezequiel Pérez-Inestrosa, Miguel Blanca, María José Torres, Javier Cañada and Dolores Pérez-Sala

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P37

Content type: Poster presentation Published on: 18 July 2014
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Abacavir forms novel cross-linking abacavir protein adducts in patients

Authors: Xiaoli Meng, Alexandre Lawrenson, Neil Berry, James Maggs, Neil French, David Back, Saye Khoo, Dean Naisbitt and Kevin Park

Citation: Clinical and Translational Allergy 2014 4(Suppl 3):P38

Content type: Poster presentation Published on: 18 July 2014
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6th Drug Hypersensitivity Meeting (DHM 6)

Meeting abstracts

Clinical and Translational Allergy

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