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  1. Review

    Allergen immunotherapy for allergic rhinoconjunctivitis: a systematic overview of systematic reviews

    The European Academy of Allergy and Clinical Immunology (EAACI) is developing Guidelines on Allergen Immunotherapy (AIT) for Allergic Rhinoconjunctivitis (ARC). To inform the development of recommendations, we...

    Ulugbek Nurmatov, Sangeeta Dhami, Stefania Arasi, Graham Roberts, Oliver Pfaar, Antonella Muraro, Ignacio J. Ansotegui, Moises Calderon, Cemal Cingi, Stephen Durham, Roy Gerth van Wijk, Susanne Halken, Eckard Hamelmann, Peter Hellings, Lars Jacobsen, Edward Knol…

    Clinical and Translational Allergy 2017 7:24

    Published on: 8 August 2017

  2. Review

    Allergen immunotherapy for allergic asthma: a systematic overview of systematic reviews

    There is clinical uncertainty about the effectiveness and safety of allergen immunotherapy (AIT) for the treatment of allergic asthma.

    Felix Asamoah, Artemisia Kakourou, Sangeeta Dhami, Susanne Lau, Ioana Agache, Antonella Muraro, Graham Roberts, Cezmi Akdis, Matteo Bonini, Ozlem Cavkaytar, Breda Flood, Kenji Izuhara, Marek Jutel, Ömer Kalayci, Oliver Pfaar and Aziz Sheikh

    Clinical and Translational Allergy 2017 7:25

    Published on: 2 August 2017

  3. Brief communication

    National clinical practice guidelines for food allergy and anaphylaxis: an international assessment

    Clinical practice guidelines are important tools to promote evidence-based clinical care, but not all countries have the capacity or infrastructure to develop these in-house. The European Academy of Allergy an...

    Asiyah Sheikh, Zakariya Sheikh, Graham Roberts, Antonella Muraro, Sangeeta Dhami and Aziz Sheikh

    Clinical and Translational Allergy 2017 7:23

    Published on: 25 July 2017

  4. Review

    Diagnosing allergic sensitizations in the third millennium: why clinicians should know allergen molecule structures

    Diagnostic tests to detect allergic sensitization were introduced at the end of the nineteenth century but only in the late 1990s did the advent of molecular allergology revolutionize the approach to the aller...

    C. Alessandri, R. Ferrara, M. L. Bernardi, D. Zennaro, L. Tuppo, I. Giangrieco, M. Tamburrini, A. Mari and M. A. Ciardiello

    Clinical and Translational Allergy 2017 7:21

    Published on: 17 July 2017

  5. Review

    Endotype-driven treatment in chronic upper airway diseases

    Rhinitis and rhinosinusitis are the two major clinical entities of chronic upper airway disease. Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) affect respectively up to 10 and 30% of the total popula...

    Glynnis De Greve, Peter W. Hellings, Wytske J. Fokkens, Benoit Pugin, Brecht Steelant and Sven F. Seys

    Clinical and Translational Allergy 2017 7:22

    Published on: 12 July 2017

  6. Research

    Health Related Quality of Life among schoolchildren aged 12–13 years in relation to food hypersensitivity phenotypes: a population-based study

    While Health Related Quality of Life has been investigated among children with IgE-mediated food allergy, less is known about quality of life among children with other types of hypersensitivity to food. The ai...

    Åsa Strinnholm, Linnéa Hedman, Anna Winberg, Sven-Arne Jansson, Viveca Lindh and Eva Rönmark

    Clinical and Translational Allergy 2017 7:20

    Published on: 3 July 2017

  7. Letter to the Editor

    Food allergy in a child with de novo KAT6A mutation

    Crying combined with miscellaneous gastrointestinal symptoms are typical symptoms of infant with food allergy, but are also common among children with abnormal neurological development. Mutations in KAT6A gene is...

    Varpu Elenius, Tuire Lähdesmäki, Marja Hietala and Tuomas Jartti

    Clinical and Translational Allergy 2017 7:19

    Published on: 22 June 2017

  8. Research

    The impact of penicillin allergy labels on antibiotic and health care use in primary care: a retrospective cohort study

    Suspected penicillin allergy (Pen-A) is often not verified by diagnostic testing. In third line penicillin allergy labels were associated with prescription of broad spectrum antibiotics, hospital stay duration...

    Tanly Su, Berna D. L. Broekhuizen, Theo J. M. Verheij and Heike Rockmann

    Clinical and Translational Allergy 2017 7:18

    Published on: 7 June 2017

  9. Review

    Multi-morbidities of allergic rhinitis in adults: European Academy of Allergy and Clinical Immunology Task Force Report

    This report has been prepared by the European Academy of Allergy and Clinical Immunology Task Force on Allergic Rhinitis (AR) comorbidities. The aim of this multidisciplinary European consensus document is t...

    C. Cingi, P. Gevaert, R. Mösges, C. Rondon, V. Hox, M. Rudenko, N. B. Muluk, G. Scadding, F. Manole, C. Hupin, W. J. Fokkens, C. Akdis, C. Bachert, P. Demoly, J. Mullol, A. Muraro…

    Clinical and Translational Allergy 2017 7:17

    Published on: 1 June 2017

  10. Meeting abstracts

    Abstracts from the 3rd International Severe Asthma Forum (ISAF)

    M. E. Ketelaar, K. Van De Kant, F. N. Dijk, E. M. M. Klaassen, N. Grotenboer, M. C. Nawijn, E. Dompeling, G. H. Koppelman, Clare Murray, Philip Foden, Lesley Lowe, Hannah Durrington, Adnan Custovic, Angela Simpson, Andrew J. Simpson, Dominick E. Shaw…

    Clinical and Translational Allergy 2017 7(Suppl 2):14

    Published on: 24 May 2017

    This article is part of a Supplement: Volume 7 Supplement 2

  11. Review

    Quality indicators for the acute and long-term management of anaphylaxis: a systematic review

    The quality of acute and long-term anaphylaxis management is variable and this contributes to the poor outcomes experienced by many patients. Clinical practice guidelines have the potential to improve outcomes...

    Sangeeta Dhami, Aadam Sheikh, Antonella Muraro, Graham Roberts, Susanne Halken, Monserat Fernandez Rivas, Margitta Worm and Aziz Sheikh

    Clinical and Translational Allergy 2017 7:15

    Published on: 24 May 2017

  12. Review

    Application of the adverse outcome pathway (AOP) concept to structure the available in vivo and in vitro mechanistic data for allergic sensitization to food proteins

    The introduction of whole new foods in a population may lead to sensitization and food allergy. This constitutes a potential public health problem and a challenge to risk assessors and managers as the existing...

    Jolanda H. M. van Bilsen, Edyta Sienkiewicz-Szłapka, Daniel Lozano-Ojalvo, Linette E. M. Willemsen, Celia M. Antunes, Elena Molina, Joost J. Smit, Barbara Wróblewska, Harry J. Wichers, Edward F. Knol, Gregory S. Ladics, Raymond H. H. Pieters, Sandra Denery-Papini, Yvonne M. Vissers, Simona L. Bavaro, Colette Larré…

    Clinical and Translational Allergy 2017 7:13

    Published on: 12 May 2017

  13. Research

    Early childhood risk factors for rhinoconjunctivitis in adolescence: a prospective birth cohort study

    Rhinoconjunctivitis is a global health problem and one of the most common chronic conditions in children. Development of rhinoconjunctivitis depends on both genetic and environmental factors. Many studies have...

    Elisabeth Soegaard Christiansen, Henrik Fomsgaard Kjaer, Esben Eller, Carsten Bindslev-Jensen, Arne Høst, Charlotte Gotthard Mortz and Susanne Halken

    Clinical and Translational Allergy 2017 7:9

    Published on: 3 April 2017

  14. Meeting abstracts

    Abstracts from the Food Allergy and Anaphylaxis Meeting 2016

    Guillaume Pouessel, Claire Claverie, Julien Labreuche, Jean-Marie Renaudin, Aimée Dorkenoo, Mireille Eb, Anne Moneret-Vautrin, Antoine Deschildre, Stephane Leteurtre, Linus Grabenhenrich, Margitta Worm, Sabine Dölle, Kathrin Scherer, Isidor Hutteger, Morten Christensen, Carsten Bindslev-Jensen…

    Clinical and Translational Allergy 2017 7(Suppl 1):10

    Published on: 30 March 2017

    This article is part of a Supplement: Volume 7 Supplement 1

  15. Research

    The state of asthma epidemiology: an overview of systematic reviews and their quality

    Recently, we have published an overview of systematic reviews in allergy epidemiology and identified asthma as the most commonly reviewed allergic disease. Building on this work, we aimed to investigate the qu...

    Jon Genuneit, Annina M. Seibold, Christian J. Apfelbacher, George N. Konstantinou, Jennifer J. Koplin, Stefania La Grutta, Kirsty Logan, Carsten Flohr and Michael R. Perkin

    Clinical and Translational Allergy 2017 7:12

    Published on: 29 March 2017

  16. Brief communication

    Low percentage of clinically relevant pistachio nut and mango co-sensitisation in cashew nut sensitised children

    Cashew nut, pistachio nut and mango belong to the Anacardiaceae family and are botanically related. Therefore, cashew nut sensitised children are frequently advised to eliminate cashew nuts and pistachio nuts fro...

    J. P. M. van der Valk, R. el Bouche, R. Gerth van Wijk, H. de Groot, H. J. Wichers, A. E. J. Dubois and N. W. de Jong

    Clinical and Translational Allergy 2017 7:8

    Published on: 20 March 2017

  17. Review

    Approach to the diagnosis of drug hypersensitivity reactions: similarities and differences between Europe and North America

    Drug hypersensitivity reactions (DHRs) affect an unknown proportion of the general population, and are an important public health problem due to their potential to cause life-threatening anaphylaxis and rare ...

    M. J. Torres, A. Romano, G. Celik, P. Demoly, D. A. Khan, E. Macy, M. Park, K. Blumenthal, W. Aberer, M. Castells, A. Barbaud, C. Mayorga and P. Bonadonna

    Clinical and Translational Allergy 2017 7:7

    Published on: 13 March 2017

  18. Research

    Galectin-3: an early predictive biomarker of modulation of airway remodeling in patients with severe asthma treated with omalizumab for 36 months

    Bronchial asthma is a heterogeneous disease characterized by three cardinal features: chronic inflammation, variable airflow obstruction, and airway hyperresponsiveness. Asthma has traditionally been defined ...

    Anna Maria Riccio, Pierluigi Mauri, Laura De Ferrari, Rossana Rossi, Dario Di Silvestre, Louise Benazzi, Alessandra Chiappori, Roberto Walter Dal Negro, Claudio Micheletto and Giorgio Walter Canonica

    Clinical and Translational Allergy 2017 7:6

    Published on: 9 March 2017

  19. Erratum

    Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)

    J. Bousquet, J. Farrell, G. Crooks, P. Hellings, E. H. Bel, M. Bewick, N. H. Chavannes, J. Correia de Sousa, A. A. Cruz, T. Haahtela, G. Joos, N. Khaltaev, J. Malva, A. Muraro, M. Nogues, S. Palkonen…

    Clinical and Translational Allergy 2017 7:5

    Published on: 20 February 2017

    The original article was published in Clinical and Translational Allergy 2016 6:29

  20. Research

    Effectiveness and safety of antihistamines up to fourfold or higher in treatment of chronic spontaneous urticaria

    Treatment with second-generation antihistamines is recommended in patients with chronic spontaneous urticaria (CSU). Some patients remain unresponsive even after up-dosing up to fourfold. Many third line treat...

    Mignon T. van den Elzen, Harmieke van Os-Medendorp, Imke van den Brink, Karin van den Hurk, Ouliana I. Kouznetsova, Alexander S. H. J. Lokin, Anna-Marijke Laheij-de Boer, Heike Röckmann, Carla A. F. M. Bruijnzeel-Koomen and André C. Knulst

    Clinical and Translational Allergy 2017 7:4

    Published on: 14 February 2017

  21. Research

    Is fruit and vegetable intake associated with asthma or chronic rhino-sinusitis in European adults? Results from the Global Allergy and Asthma Network of Excellence (GA2LEN) Survey

    Fruits and vegetables are rich in compounds with proposed antioxidant, anti-allergic and anti-inflammatory properties, which could contribute to reduce the prevalence of asthma and allergic diseases.

    Vanessa Garcia-Larsen, Rhonda Arthur, James F. Potts, Peter H. Howarth, Matti Ahlström, Tari Haahtela, Carlos Loureiro, Ana Todo Bom, Grzegorz Brożek, Joanna Makowska, Marek L. Kowalski, Trine Thilsing, Thomas Keil, Paolo M. Matricardi, Kjell Torén, Thibaut van Zele…

    Clinical and Translational Allergy 2017 7:3

    Published on: 27 January 2017

  22. Review

    Looking forward to new targeted treatments for chronic spontaneous urticaria

    The introduction of omalizumab to the management of chronic spontaneous urticaria (CSU) has markedly improved the therapeutic possibilities for both, patients and physicians dealing with this disabling disease...

    Emek Kocatürk, Marcus Maurer, Martin Metz and Clive Grattan

    Clinical and Translational Allergy 2017 7:1

    Published on: 10 January 2017

    The Erratum to this article has been published in Clinical and Translational Allergy 2017 7:11

  23. Letter to the Editor

    Three cases of anaphylaxis following injection of a depot corticosteroid with evidence of IgE sensitization to macrogols rather than the active steroid

    We present three cases with anaphylaxis after injection of a depot corticosteroid. First, the steroid was suspected as the elicitor, but after evaluation the excipient macrogol was found to be the elicitor. On...

    Nicolaj Brandt, Lene H. Garvey, Ulla Bindslev-Jensen, Henrik Fomsgaard Kjaer, Carsten Bindslev-Jensen and Charlotte G. Mortz

    Clinical and Translational Allergy 2017 7:2

    Published on: 10 January 2017

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