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  1. The editors of Clinical and Translational Allergy would like to thank all of our reviewers who have contributed to the journal in Volume 3 (2013).

    Authors: Clive Grattan
    Citation: Clinical and Translational Allergy 2014 4:5
    Content type: Reviewer acknowledgement Published on:

  2. Oil body-associated allergens such as oleosins have been reported for important allergenic foods such as peanut, sesame and hazelnut. Here we investigate whether oil body associated proteins (OAPs) are linked ...

    Authors: Laurian Zuidmeer-Jongejan, Montserrat Fernández-Rivas, Marcel GT Winter, Jaap H Akkerdaas, Colin Summers, Ans Lebens, André C Knulst, Piet Schilte, Peter Briza, Gabriele Gadermaier and Ronald van Ree
    Citation: Clinical and Translational Allergy 2014 4:4
    Content type: Research Published on:

  3. Th2-type T cell response has a considerable role in atopic diseases. The involvement of Th17 and IL-17 in atopy process provided new understanding of allergic diseases. Bronchial hyperresponsiveness is quite c...

    Authors: Vanya M Tsvetkova-Vicheva, Svetla P Gecheva, Regina Komsa-Penkova, Angelika S Velkova and Tcvetan H Lukanov
    Citation: Clinical and Translational Allergy 2014 4:3
    Content type: Research Published on:

  4. Interleukin-10 (IL-10) is a negative regulator of immune responses and was previously shown to be expressed by human nasal endothelial cells, while the adhesion molecule MECA-79 plays a role in trans-endotheli...

    Authors: Barbara Muller, Danielle van Egmond, Esther JJ de Groot, Wytske J Fokkens and Cornelis M van Drunen
    Citation: Clinical and Translational Allergy 2014 4:2
    Content type: Research Published on:

  5. There is promising but conflicting evidence to recommend the addition of probiotics to foods for prevention and treatment of allergy. Based on previous studies with fermented milk containing Lactobacillus paracas...

    Authors: Yannick Perrin, Sophie Nutten, Régine Audran, Bernard Berger, Rodrigo Bibiloni, Jacqueline Wassenberg, Nathalie Barbier, Vincent Aubert, Julie Moulin, Anurag Singh, Corinne Magliola, Annick Mercenier and François Spertini
    Citation: Clinical and Translational Allergy 2014 4:1
    Content type: Research Published on:

  6. Double-blind, placebo-controlled (DBPC) trials are the gold standard for demonstrating clinical efficacy and tolerability. The placebo effect, although an important feature in placebo-controlled studies, has n...

    Authors: Annemie Narkus, Ulrike Lehnigk, Dietrich Haefner, Regine Klinger, Oliver Pfaar and Margitta Worm
    Citation: Clinical and Translational Allergy 2013 3:42
    Content type: Research Published on:

  7. Avoidance of food allergens requires adapting dietetic habits, changing nutritional approach. A restriction of food choice can result in a monotonous diet and impact social life. This study investigated the im...

    Authors: Laura Polloni, Alice Toniolo, Francesca Lazzarotto, Ileana Baldi, Francesca Foltran, Dario Gregori and Antonella Muraro
    Citation: Clinical and Translational Allergy 2013 3:41
    Content type: Research Published on:

  8. One of the IL-17 family members, IL-25, has been implicated with the initiation and amplification of Th2 responses in animal models and has been associated with airway hyper-reactivity. The involvement of IL-2...

    Authors: Joost A Aalberse, Anders O van Thuijl, Yolanda Meijer, Wilco de Jager, Tjitske van der Palen-Merkus, Aline B Sprikkelman, Maarten O Hoekstra, Berent J Prakken and Femke van Wijk
    Citation: Clinical and Translational Allergy 2013 3:40
    Content type: Brief communication Published on:

  9. The incidence of food allergy is such that most schools will be attended by at least one food allergic child, obliging school personnel to cope with cases at risk of severe allergic reactions. Schools need to ...

    Authors: Laura Polloni, Francesca Lazzarotto, Alice Toniolo, Giorgia Ducolin and Antonella Muraro
    Citation: Clinical and Translational Allergy 2013 3:39
    Content type: Research Published on:

  10. Food-induced anaphylaxis (FIA) in adults is often insufficiently diagnosed. One reason is related to the presence of co-factors like exercise, alcohol, additives and non-steroidal anti-inflammatory drugs. The ...

    Authors: Stephanie Hompes, Sabine Dölle, Josefine Grünhagen, Linus Grabenhenrich and Margitta Worm
    Citation: Clinical and Translational Allergy 2013 3:38
    Content type: Brief communication Published on:

  11. Fractional exhaled nitric oxide (FeNO) is a surrogate marker of eosinophilic airway inflammation and good predictor of corticosteroid response.

    Authors: David Price, Dermot Ryan, Annie Burden, Julie Von Ziegenweidt, Shuna Gould, Daryl Freeman, Kevin Gruffydd-Jones, Anne Copland, Clifford Godley, Alison Chisholm and Mike Thomas
    Citation: Clinical and Translational Allergy 2013 3:37
    Content type: Research Published on:

  12. It is not exactly known why certain food proteins are more likely to sensitize. One of the characteristics of most food allergens is that they are stable to the acidic and proteolytic conditions in the digesti...

    Authors: Jolanda HM Van Bilsen, Léon MJ Knippels, André H Penninks, Willem F Nieuwenhuizen, Harmen HJ De Jongh and Stef J Koppelman
    Citation: Clinical and Translational Allergy 2013 3:36
    Content type: Brief communication Published on:

  13. Insect venom allergy (IVA) may result in the most severe systemic reactions seen in allergology. The only potentially curative treatment option is venom immunotherapy (VIT) over 3 to 5 years. This treatment is...

    Authors: Marek Niedoszytko, Marta Gruchała-Niedoszytko and Ewa Jassem
    Citation: Clinical and Translational Allergy 2013 3:35
    Content type: Review Published on:

  14. The usefulness of peanut specific IgE levels for diagnosing peanut allergy has not been studied in primary and secondary care where most cases of suspected peanut allergy are being evaluated. We aimed to deter...

    Authors: Wilma J van Veen, Lambert D Dikkeschei, Graham Roberts and Paul LP Brand
    Citation: Clinical and Translational Allergy 2013 3:34
    Content type: Research Published on:

  15. Allergic Rhinitis is an inflammatory disease which is characterised by burdensome nasal and/or ocular symptoms. This study aimed to assess the impact of symptoms (number of symptom-free days (SFD) and Quality ...

    Authors: Mark Small, James Piercy, Pascal Demoly and Helen Marsden
    Citation: Clinical and Translational Allergy 2013 3:33
    Content type: Research Published on:

  16. Steady progress in our understanding of the genetic basis of autoinflammatory diseases has been made over the past 16 years. Since the discovery of the familial Me diterranean f ev er gene MEFV (also known as mar...

    Authors: Ariane Standing, Ebun Omoyinmi and Paul Brogan
    Citation: Clinical and Translational Allergy 2013 3:32
    Content type: Review Published on:

  17. Buying behaviours of food-allergic consumers can affect the risk they incur. An online survey was undertaken to understand the characteristics and buying behaviours of food-allergic consumers in Great Britain ...

    Authors: Stella Anne Cochrane, M Hazel Gowland, David Sheffield and René Wilfrid Robert Crevel
    Citation: Clinical and Translational Allergy 2013 3:31
    Content type: Research Published on:

  18. Subcutaneous specific immunotherapy (SCIT) is an effective treatment attenuatingthe progression of allergic asthma. To date, there is a lack of studiesinvestigating the economic consequences of SCIT on health ...

    Authors: Thomas Reinhold, Julia Ostermann, Susanne Thum-Oltmer and Bernd Brüggenjürgen
    Citation: Clinical and Translational Allergy 2013 3:30
    Content type: Research Published on:

  19. Omalizumab, is a humanized anti-IgE monoclonal antibody used to treat allergic asthma. Decreased serum IgE levels, lower eosinophil and B cell counts have been noted as a result of treatment. In vitro studies ...

    Authors: Marcia A Chan, Nicole M Gigliotti, Abby L Dotson and Lanny J Rosenwasser
    Citation: Clinical and Translational Allergy 2013 3:29
    Content type: Research Published on:

  20. Corticosteroids are the first-line therapy for asthma; however, the effect of corticosteroids on the innate immune system remains unclear. This study’s objective was to evaluate the effect of inhaled corticost...

    Authors: Carmen Lívia Faria da Silva-Martins, Shirley Claudino Couto and Maria Imaculada Muniz-Junqueira
    Citation: Clinical and Translational Allergy 2013 3:28
    Content type: Research Published on:

  21. Subcutaneous immunotherapy with high dose grass pollen (typically microgram quantities) was first described over 100 years ago. This treatment suppresses allergen-induced cutaneous late responses, with lesser ...

    Authors: Anna Slovick, Abdel Douiri, Joanna Kelly, Andrea Guerra, Rachel Muir, Konstantinos Tsioulos, Caroline Murphy, Mohamed H Shamji, Sun Ying, Stephen R Durham and Stephen J Till
    Citation: Clinical and Translational Allergy 2013 3:27
    Content type: Study protocol Published on:

  22. Orofacial granulomatosis (OFG) causes chronic, disfiguring, granulomatous inflammation of the lips and oral mucosa. A proportion of cases have co-existing intestinal Crohn’s disease (CD). The pathogenesis is u...

    Authors: Pritash Patel, Jonathan Brostoff, Helen Campbell, Rishi M Goel, Kirstin Taylor, Shuvra Ray, Miranda Lomer, Michael Escudier, Stephen Challacombe, Jo Spencer and Jeremy Sanderson
    Citation: Clinical and Translational Allergy 2013 3:26
    Content type: Research Published on:

  23. Venom allergy is a rare but life-threatening disease and may have a considerable impact on the health-related quality of life (HRQoL) of patients, especially children. This paper presents development of the HR...

    Authors: Ewa Cichocka-Jarosz, Piotr Brzyski, Beata Tobiasz-Adamczyk, Grzegorz Lis and Jacek J Pietrzyk
    Citation: Clinical and Translational Allergy 2013 3:25
    Content type: Research Published on:

Clinical and Translational Allergy

ISSN: 2045-7022

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