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  1. There is clinical uncertainty about the effectiveness and safety of allergen immunotherapy (AIT) for the treatment of allergic asthma.

    Authors: Felix Asamoah, Artemisia Kakourou, Sangeeta Dhami, Susanne Lau, Ioana Agache, Antonella Muraro, Graham Roberts, Cezmi Akdis, Matteo Bonini, Ozlem Cavkaytar, Breda Flood, Kenji Izuhara, Marek Jutel, Ömer Kalayci, Oliver Pfaar and Aziz Sheikh

    Citation: Clinical and Translational Allergy 2017 7:25

    Content type: Review

    Published on:

  2. Clinical practice guidelines are important tools to promote evidence-based clinical care, but not all countries have the capacity or infrastructure to develop these in-house. The European Academy of Allergy an...

    Authors: Asiyah Sheikh, Zakariya Sheikh, Graham Roberts, Antonella Muraro, Sangeeta Dhami and Aziz Sheikh

    Citation: Clinical and Translational Allergy 2017 7:23

    Content type: Brief communication

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  3. Diagnostic tests to detect allergic sensitization were introduced at the end of the nineteenth century but only in the late 1990s did the advent of molecular allergology revolutionize the approach to the aller...

    Authors: C. Alessandri, R. Ferrara, M. L. Bernardi, D. Zennaro, L. Tuppo, I. Giangrieco, M. Tamburrini, A. Mari and M. A. Ciardiello

    Citation: Clinical and Translational Allergy 2017 7:21

    Content type: Review

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  4. Rhinitis and rhinosinusitis are the two major clinical entities of chronic upper airway disease. Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) affect respectively up to 10 and 30% of the total popula...

    Authors: Glynnis De Greve, Peter W. Hellings, Wytske J. Fokkens, Benoit Pugin, Brecht Steelant and Sven F. Seys

    Citation: Clinical and Translational Allergy 2017 7:22

    Content type: Review

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  5. While Health Related Quality of Life has been investigated among children with IgE-mediated food allergy, less is known about quality of life among children with other types of hypersensitivity to food. The ai...

    Authors: Åsa Strinnholm, Linnéa Hedman, Anna Winberg, Sven-Arne Jansson, Viveca Lindh and Eva Rönmark

    Citation: Clinical and Translational Allergy 2017 7:20

    Content type: Research

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  6. Crying combined with miscellaneous gastrointestinal symptoms are typical symptoms of infant with food allergy, but are also common among children with abnormal neurological development. Mutations in KAT6A gene is...

    Authors: Varpu Elenius, Tuire Lähdesmäki, Marja Hietala and Tuomas Jartti

    Citation: Clinical and Translational Allergy 2017 7:19

    Content type: Letter to the Editor

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  7. Suspected penicillin allergy (Pen-A) is often not verified by diagnostic testing. In third line penicillin allergy labels were associated with prescription of broad spectrum antibiotics, hospital stay duration...

    Authors: Tanly Su, Berna D. L. Broekhuizen, Theo J. M. Verheij and Heike Rockmann

    Citation: Clinical and Translational Allergy 2017 7:18

    Content type: Research

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  8. This report has been prepared by the European Academy of Allergy and Clinical Immunology Task Force on Allergic Rhinitis (AR) comorbidities. The aim of this multidisciplinary European consensus document is t...

    Authors: C. Cingi, P. Gevaert, R. Mösges, C. Rondon, V. Hox, M. Rudenko, N. B. Muluk, G. Scadding, F. Manole, C. Hupin, W. J. Fokkens, C. Akdis, C. Bachert, P. Demoly, J. Mullol, A. Muraro…

    Citation: Clinical and Translational Allergy 2017 7:17

    Content type: Review

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  9. The quality of acute and long-term anaphylaxis management is variable and this contributes to the poor outcomes experienced by many patients. Clinical practice guidelines have the potential to improve outcomes...

    Authors: Sangeeta Dhami, Aadam Sheikh, Antonella Muraro, Graham Roberts, Susanne Halken, Monserat Fernandez Rivas, Margitta Worm and Aziz Sheikh

    Citation: Clinical and Translational Allergy 2017 7:15

    Content type: Review

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  10. Authors: M. E. Ketelaar, K. Van De Kant, F. N. Dijk, E. M. M. Klaassen, N. Grotenboer, M. C. Nawijn, E. Dompeling, G. H. Koppelman, Clare Murray, Philip Foden, Lesley Lowe, Hannah Durrington, Adnan Custovic, Angela Simpson, Andrew J. Simpson, Dominick E. Shaw…

    Citation: Clinical and Translational Allergy 2017 7(Suppl 2):14

    Content type: Meeting abstracts

    Published on:

    This article is part of a Supplement: Volume 7 Supplement 2

  11. The variability of symptoms observed in patients with respiratory allergy often hampers classification based on the criteria proposed in guidelines on rhinitis and asthma.

    Authors: Ana M. Navarro, Julio Delgado, Rosa M. Muñoz-Cano, M. Teresa Dordal, Antonio Valero and Santiago Quirce

    Citation: Clinical and Translational Allergy 2017 7:16

    Content type: Research

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  12. The introduction of whole new foods in a population may lead to sensitization and food allergy. This constitutes a potential public health problem and a challenge to risk assessors and managers as the existing...

    Authors: Jolanda H. M. van Bilsen, Edyta Sienkiewicz-Szłapka, Daniel Lozano-Ojalvo, Linette E. M. Willemsen, Celia M. Antunes, Elena Molina, Joost J. Smit, Barbara Wróblewska, Harry J. Wichers, Edward F. Knol, Gregory S. Ladics, Raymond H. H. Pieters, Sandra Denery-Papini, Yvonne M. Vissers, Simona L. Bavaro, Colette Larré…

    Citation: Clinical and Translational Allergy 2017 7:13

    Content type: Review

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  14. Rhinoconjunctivitis is a global health problem and one of the most common chronic conditions in children. Development of rhinoconjunctivitis depends on both genetic and environmental factors. Many studies have...

    Authors: Elisabeth Soegaard Christiansen, Henrik Fomsgaard Kjaer, Esben Eller, Carsten Bindslev-Jensen, Arne Høst, Charlotte Gotthard Mortz and Susanne Halken

    Citation: Clinical and Translational Allergy 2017 7:9

    Content type: Research

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  15. Authors: Guillaume Pouessel, Claire Claverie, Julien Labreuche, Jean-Marie Renaudin, Aimée Dorkenoo, Mireille Eb, Anne Moneret-Vautrin, Antoine Deschildre, Stephane Leteurtre, Linus Grabenhenrich, Margitta Worm, Sabine Dölle, Kathrin Scherer, Isidor Hutteger, Morten Christensen, Carsten Bindslev-Jensen…

    Citation: Clinical and Translational Allergy 2017 7(Suppl 1):10

    Content type: Meeting abstracts

    Published on:

    This article is part of a Supplement: Volume 7 Supplement 1

  16. Recently, we have published an overview of systematic reviews in allergy epidemiology and identified asthma as the most commonly reviewed allergic disease. Building on this work, we aimed to investigate the qu...

    Authors: Jon Genuneit, Annina M. Seibold, Christian J. Apfelbacher, George N. Konstantinou, Jennifer J. Koplin, Stefania La Grutta, Kirsty Logan, Carsten Flohr and Michael R. Perkin

    Citation: Clinical and Translational Allergy 2017 7:12

    Content type: Research

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  17. Cashew nut, pistachio nut and mango belong to the Anacardiaceae family and are botanically related. Therefore, cashew nut sensitised children are frequently advised to eliminate cashew nuts and pistachio nuts fro...

    Authors: J. P. M. van der Valk, R. el Bouche, R. Gerth van Wijk, H. de Groot, H. J. Wichers, A. E. J. Dubois and N. W. de Jong

    Citation: Clinical and Translational Allergy 2017 7:8

    Content type: Brief communication

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  18. Drug hypersensitivity reactions (DHRs) affect an unknown proportion of the general population, and are an important public health problem due to their potential to cause life-threatening anaphylaxis and rare ...

    Authors: M. J. Torres, A. Romano, G. Celik, P. Demoly, D. A. Khan, E. Macy, M. Park, K. Blumenthal, W. Aberer, M. Castells, A. Barbaud, C. Mayorga and P. Bonadonna

    Citation: Clinical and Translational Allergy 2017 7:7

    Content type: Review

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  19. Bronchial asthma is a heterogeneous disease characterized by three cardinal features: chronic inflammation, variable airflow obstruction, and airway hyperresponsiveness. Asthma has traditionally been defined ...

    Authors: Anna Maria Riccio, Pierluigi Mauri, Laura De Ferrari, Rossana Rossi, Dario Di Silvestre, Louise Benazzi, Alessandra Chiappori, Roberto Walter Dal Negro, Claudio Micheletto and Giorgio Walter Canonica

    Citation: Clinical and Translational Allergy 2017 7:6

    Content type: Research

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  20. Authors: J. Bousquet, J. Farrell, G. Crooks, P. Hellings, E. H. Bel, M. Bewick, N. H. Chavannes, J. Correia de Sousa, A. A. Cruz, T. Haahtela, G. Joos, N. Khaltaev, J. Malva, A. Muraro, M. Nogues, S. Palkonen…

    Citation: Clinical and Translational Allergy 2017 7:5

    Content type: Erratum

    Published on:

    The original article was published in Clinical and Translational Allergy 2016 6:29

  21. Treatment with second-generation antihistamines is recommended in patients with chronic spontaneous urticaria (CSU). Some patients remain unresponsive even after up-dosing up to fourfold. Many third line treat...

    Authors: Mignon T. van den Elzen, Harmieke van Os-Medendorp, Imke van den Brink, Karin van den Hurk, Ouliana I. Kouznetsova, Alexander S. H. J. Lokin, Anna-Marijke Laheij-de Boer, Heike Röckmann, Carla A. F. M. Bruijnzeel-Koomen and André C. Knulst

    Citation: Clinical and Translational Allergy 2017 7:4

    Content type: Research

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  22. Fruits and vegetables are rich in compounds with proposed antioxidant, anti-allergic and anti-inflammatory properties, which could contribute to reduce the prevalence of asthma and allergic diseases.

    Authors: Vanessa Garcia-Larsen, Rhonda Arthur, James F. Potts, Peter H. Howarth, Matti Ahlström, Tari Haahtela, Carlos Loureiro, Ana Todo Bom, Grzegorz Brożek, Joanna Makowska, Marek L. Kowalski, Trine Thilsing, Thomas Keil, Paolo M. Matricardi, Kjell Torén, Thibaut van Zele…

    Citation: Clinical and Translational Allergy 2017 7:3

    Content type: Research

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  23. We present three cases with anaphylaxis after injection of a depot corticosteroid. First, the steroid was suspected as the elicitor, but after evaluation the excipient macrogol was found to be the elicitor. On...

    Authors: Nicolaj Brandt, Lene H. Garvey, Ulla Bindslev-Jensen, Henrik Fomsgaard Kjaer, Carsten Bindslev-Jensen and Charlotte G. Mortz

    Citation: Clinical and Translational Allergy 2017 7:2

    Content type: Letter to the Editor

    Published on:

  24. The introduction of omalizumab to the management of chronic spontaneous urticaria (CSU) has markedly improved the therapeutic possibilities for both, patients and physicians dealing with this disabling disease...

    Authors: Emek Kocatürk, Marcus Maurer, Martin Metz and Clive Grattan

    Citation: Clinical and Translational Allergy 2017 7:1

    Content type: Review

    Published on:

    The Erratum to this article has been published in Clinical and Translational Allergy 2017 7:11

  25. The Allergic Rhinitis and its Impact on Asthma (ARIA) initiative commenced during a World Health Organization workshop in 1999. The initial goals were (1) to propose a new allergic rhinitis classification, (2)...

    Authors: J. Bousquet, P. W. Hellings, I. Agache, A. Bedbrook, C. Bachert, K. C. Bergmann, M. Bewick, C. Bindslev-Jensen, S. Bosnic-Anticevitch, C. Bucca, D. P. Caimmi, P. A. M. Camargos, G. W. Canonica, T. Casale, N. H. Chavannes, A. A. Cruz…

    Citation: Clinical and Translational Allergy 2016 6:47

    Content type: Review

    Published on:

    The Correction to this article has been published in Clinical and Translational Allergy 2019 9:53

  26. Challenge tests for food-dependent exercise-induced anaphylaxis (FDEIA) carry some risk and have a high rate of false negatives. Our aim was to explore the usefulness of an in vitro immunodepletion assay and a...

    Authors: Diana Margarida Gonçalves Solha Pereira da Silva, Teresa Maria Silva Vieira, Ana Maria Alves Pereira, André Miguel Afonso de Sousa Moreira and José Luís Dias Delgado

    Citation: Clinical and Translational Allergy 2016 6:46

    Content type: Brief communication

    Published on:

  27. Sensitization to hazelnut (HN) is frequent and requires clarification to determine whether this sensitization is clinically relevant. The aim of this study was to investigate basophil activation profiles in HN...

    Authors: Bianca Lötzsch, Sabine Dölle, Stefan Vieths and Margitta Worm

    Citation: Clinical and Translational Allergy 2016 6:45

    Content type: Research

    Published on:

  28. Although total IgE levels have been proposed as a biomarker for disease severity in atopic dermatitis (AD) and are increased in the majority of AD patients, they do not correlate with disease severity during s...

    Authors: J. L. Thijs, K. Knipping, C. A. F. Bruijnzeel-Koomen, J. Garssen, M. S. de Bruin-Weller and D. J. Hijnen

    Citation: Clinical and Translational Allergy 2016 6:44

    Content type: Brief communication

    Published on:

  29. The European Academy of Allergy and Clinical Immunology (EAACI) Junior Members (JM) comprise the largest EAACI section with around 4000 clinicians and scientists under 35 years of age working in the field of a...

    Authors: Peter Valentin Tomazic, Anke Graessel, Diana Silva, Ibon Eguiluz-Gracia, George V. Guibas, Clive Grattan, Jean Bousquet and Olympia Tsilochristou

    Citation: Clinical and Translational Allergy 2016 6:43

    Content type: Editorial

    Published on:

  30. Allergic diseases often occur early in life and persist throughout life. This life-course perspective should be considered in allergen immunotherapy. In particular it is essential to understand whether this al...

    Authors: M. A. Calderon, P. Demoly, T. Casale, C. A. Akdis, C. Bachert, M. Bewick, B. M. Bilò, B. Bohle, S. Bonini, A. Bush, D. P. Caimmi, G. W. Canonica, V. Cardona, A. M. Chiriac, L. Cox, A. Custovic…

    Citation: Clinical and Translational Allergy 2016 6:41

    Content type: Review

    Published on:

  31. WORKSHOP 4: Challenging clinical scenarios (CS01–CS06)

    Authors: S. Tolga Yavuz, Ozan Koc, Ali Gungor, Faysal Gok, Jessica Hawley, Christopher O’Brien, Matthew Thomas, Malcolm Brodlie, Louise Michaelis, Inês Mota, Ângela Gaspar, Susana Piedade, Graça Sampaio, José Geraldo Dias, Miguel Paiva, Mário Morais-Almeida…

    Citation: Clinical and Translational Allergy 2016 6(Suppl 1):42

    Content type: Meeting Abstracts

    Published on:

    This article is part of a Supplement: Volume 6 Supplement 1

  33. Multicentre trials investigating food allergies by double blind placebo controlled food challenges (DBPCFC) need standardized procedures, challenge meals and evaluation criteria. We aimed at developing a stand...

    Authors: R. Treudler, A. Franke, A. Schmiedeknecht, B. K. Ballmer-Weber, M. Worm, T. Werfel, U. Jappe, T. Biedermann, J. Schmitt, R. Brehler, A. Kleinheinz, J. Kleine-Tebbe, H. Brüning, F. Ruëff, J. Ring, J. Saloga…

    Citation: Clinical and Translational Allergy 2016 6:39

    Content type: Research

    Published on:

  34. ORAL ABSTRACTS

    Authors: Christiane Hilger, Kyra Swiontek, Jörg Fischer, François Hentges, Christiane Lehners, Martine Morisset, Bernadette Eberlein, Tilo Biedermann, Markus Ollert, Sabrina Wildner, Teresa Stemeseder, Regina Freier, Peter Briza, Roland Lang, Eva Batanero, Mayte Villalba…

    Citation: Clinical and Translational Allergy 2016 6(Suppl 2):38

    Content type: Meeting abstracts

    Published on:

    This article is part of a Supplement: Volume 6 Supplement 2

  35. Cow’s milk, hen’s egg and wheat are staple foods in a typical western diet. Despite the ubiquity of these foods, the impact of staple food allergy on health-related quality of life (HRQL) amongst adolescents i...

    Authors: Jennifer Lisa Penner Protudjer, Sven-Arne Jansson, Roelinde Middelveld, Eva Östblom, Sven-Erik Dahlén, Marianne Heibert Arnlind, Ulf Bengtsson, Ingrid Kallström-Bengtsson, Birgitta Marklund, Georgios Rentzos, Ann-Charlotte Sundqvist, Johanna Åkerström and Staffan Ahlstedt

    Citation: Clinical and Translational Allergy 2016 6:37

    Content type: Research

    Published on:

  37. Asthma affects an estimated 300 million people worldwide with the condition associated with significant healthcare utilisation costs and a large impact on patient quality of life. The SQ® HDM SLIT-tablet (ACARIZA...

    Authors: J. Hahn-Pedersen, M. Worm, W. Green, J. Nørgaard Andreasen and M. Taylor

    Citation: Clinical and Translational Allergy 2016 6:35

    Content type: Brief communication

    Published on:

  38. Patients can be tested for IgE sensitivities with in vivo or in vitro testing, but patients’ experiences of different allergy test modalities have not been studied. The objective of this study was to investiga...

    Authors: Clare E. Brown, Christina J. Jones, Laura Stuttaford, Annalee Robertson, Rabia S. Rashid and Helen E. Smith

    Citation: Clinical and Translational Allergy 2016 6:34

    Content type: Brief communication

    Published on:

  39. Oral Abstracts

    Authors: Daniel F. Carr, Wen-Hung Chung, Rosalind E. Jenkiins, Mas Chaponda, Gospel Nwikue, Elena M. Cornejo Castro, Daniel J. Antoine, Munir Pirmohamed, Natascha Wuillemin, Dolores Dina, Klara K. Eriksson, Daniel Yerly, Rebecca Pavlos, Elizabeth Mckinnin, David Ostrov, Bjoern Peters…

    Citation: Clinical and Translational Allergy 2016 6(Suppl 3):31

    Content type: Meeting abstracts

    Published on:

    This article is part of a Supplement: Volume 6 Supplement 3

  40. Poster walk 11: miscellaneous drug hypersensitivity 2 (P92–P94, P96–P101)

    Authors: Javier Dionicio Elera, Cosmin Boteanu, Maria Aranzazu Jimenez Blanco, Rosario Gonzalez-Mendiola, Irene Carrasco García, Antonio Alvarez, Jose Julio Laguna Martinez, Jaume Martí Garrido, Carla Torán Barona, Carolina Perales Chorda, Ramón López Salgueiro, Miguel Díaz Palacios, Dolores Hernández Fernández De Rojas, Emre Ali Acar, Ayse Aktas, Aylin Türel Ermertcan…

    Citation: Clinical and Translational Allergy 2016 6(Suppl 3):30

    Content type: Meeting abstracts

    Published on:

    This article is part of a Supplement: Volume 6 Supplement 3

  41. The results of studies on the associations of childhood excessive weight/obesity and physical activity with atopic sensitization and atopic diseases are inconsistent. We studied the associations of anthropomet...

    Authors: Kristine Kjer Byberg, Geir Egil Eide, Michele R. Forman, Pétur Benedikt Júlíusson and Knut Øymar

    Citation: Clinical and Translational Allergy 2016 6:33

    Content type: Research

    Published on:

  42. Patients with chronic idiopathic/spontaneous urticaria (CIU/CSU) report difficulty with sleep.

    Authors: Ana M. Gimenéz-Arnau, Sheldon Spector, Evgeniya Antonova, Benjamin Trzaskoma, Karin Rosén, Theodore A. Omachi, Donald Stull, Maria-Magdalena Balp and Thomas Murphy

    Citation: Clinical and Translational Allergy 2016 6:32

    Content type: Research

    Published on:

  43. Atopic diseases including asthma, rhinitis and eczema have increased in the second half of the past century. This has been well studied among children and adolescents but with the exception of asthma to a muc...

    Authors: Erik P. Rönmark, Linda Ekerljung, Roxana Mincheva, Sigrid Sjölander, Stig Hagstad, Göran Wennergren, Eva Rönmark, Jan Lötvall and Bo Lundbäck

    Citation: Clinical and Translational Allergy 2016 6:28

    Content type: Research

    Published on:

  44. Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respirato...

    Authors: J. Bousquet, J. Farrell, G. Crooks, P. Hellings, E. H. Bel, M. Bewick, N. H. Chavannes, J. Correia de Sousa, A. A. Cruz, T. Haahtela, G. Joos, N. Khaltaev, J. Malva, A. Muraro, M. Nogues, S. Palkonen…

    Citation: Clinical and Translational Allergy 2016 6:29

    Content type: Review

    Published on:

    The Erratum to this article has been published in Clinical and Translational Allergy 2017 7:5

  45. The Probiotics in Prevention of Allergy among Children in Trondheim (ProPACT) study, a randomised, placebo controlled trial, demonstrated that maternal supplementation with probiotic milk reduced the incidence...

    Authors: Melanie Rae Simpson, Anne Dorthea Bjerkenes Rø, Øystein Grimstad, Roar Johnsen, Ola Storrø and Torbjørn Øien

    Citation: Clinical and Translational Allergy 2016 6:27

    Content type: Research

    Published on:

  46. Persulphates from hair bleaching products are considered the major cause of occupational-rhinitis and asthma in hairdressers. The specific inhalation challenge (SIC) is considered ‘reference standard’ for diag...

    Authors: M. H. Foss-Skiftesvik, L. Winther, H. F. Mosbech, P. S. Skov, M. S. Opstrup, H. Søsted, C. Zachariae, J. D. Johansen and C. R. Johnsen

    Citation: Clinical and Translational Allergy 2016 6:26

    Content type: Research

    Published on:

  47. Non immunoglobulin E (IgE) mediated allergies affecting the gastrointestinal tract require an elimination diet to aid diagnosis. The elimination diet may entail multiple food eliminations that contribute signi...

    Authors: Rosan Meyer, Claire De Koker, Robert Dziubak, Heather Godwin, Gloria Dominguez-Ortega, Adriana Chebar Lozinsky, Ana-Kristina Skrapac, Yara Gholmie, Kate Reeve and Neil Shah

    Citation: Clinical and Translational Allergy 2016 6:25

    Content type: Research

    Published on:

  48. The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for IgE-mediated food allergy. We seek to critically asses...

    Authors: Sangeeta Dhami, Ulugbek Nurmatov, Giovanni Battista Pajno, Montserrat Fernandez-Rivas, Antonella Muraro, Graham Roberts, Cezmi Akdis, Montserrat Alvaro-Lozano, Kirsten Beyer, Carsten Bindslev-Jensen, Wesley Burks, George du Toit, Motohiro Ebisawa, Philippe Eigenmann, Edward Knol, Mika Makela…

    Citation: Clinical and Translational Allergy 2016 6:24

    Content type: Study protocol

    Published on:

    The Erratum to this article has been published in Clinical and Translational Allergy 2017 7:31

  49. Profilin sensitisation is considered a diagnostic confounding factor in areas where patients are exposed to multiple pollens. The aim of this study is to assess pollen sensitisation profiles in adults and chil...

    Authors: Nieves Segura, Teresa Abos, José A. Compaired, Esther Compés, Isabel Guallar, Manuel Morales, Susana Monzón, José Mozota, Pilar Muñoz, Jesús Pola, Macarena Quintana, Beatriz Rojas, Sara San Juan, Felicitas Villa, Cristina Zapata, Lucía Jimeno…

    Citation: Clinical and Translational Allergy 2016 6:23

    Content type: Research

    Published on:

  50. Patients often report adverse reactions to wheat. Interpretation of sensitization to wheat pollen and flour with/without sensitization to grass pollen is a clinical problem.

    Authors: Carina Venter, Kate Maslin, Syed Hasan Arshad, Veeresh Patil, Jane Grundy, Gillian Glasbey, Roger Twiselton and Taraneh Dean

    Citation: Clinical and Translational Allergy 2016 6:22

    Content type: Brief communication

    Published on:

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