| All participants | Lost to follow up (2 years) | Eligible for DBPCFC | ||
---|---|---|---|---|---|
Not challenged | Challenged | Confirmed food hypersensitivity | |||
n | 1140 | 317 | 15 | 55 | 41 |
Baseline characteristics | |||||
 Caucasian ethnicity | 1093 (95.8 %) | 304 (96.0 %) | 11 (73.3 %) | 50 (90.9 %) | 39 (95.1 %) |
 Smoking during pregnancy | 70 (6.1 %) | 45 (14.2 %) | 0 (0.0 %) | 1 (1.8 %) | 1 (2.4 %) |
 Mothers’ mean age, years | 31.9 (5.2) | 30.0 (5.8) | 31.9 (5.2) | 32.0 (5.5) | 31.6 (5.3) |
 Fathers’ mean age, years | 34.1 (5.7) | 32.6 (6.4) | 33.9 (5.1) | 33.9 (4.5) | 33.2 (4.6) |
 Highest education of parents | |||||
  Low (up to 12y) | 220 (19.3 %) | 86 (27.2 %) | 4 (26.7 %) | 9 (16.4 %) | 7 (17.1 %) |
  Intermediate (>12 years, e.g. college) | 331 (29.0 %) | 96 (30.2 %) | 3 (20.0 %) | 19 (34.5 %) | 13 (31.7 %) |
  High (e.g. university) | 565 (49.6 %) | 121 (38.3 %) | 8 (53.3 %) | 27 (49.1 %) | 21 (51.2 %) |
 Allergies in family | |||||
  Maternal atopy (A, AR or E) | 765 (67.1 %) | 210 (66.4 %) | 13 (86.7 %) | 48 (87.3 %) | 36 (87.8 %) |
  Paternal atopy (A, AR or E) | 610 (53.5 %) | 170 (53.7 %) | 11 (73.3 %) | 30 (54.5 %) | 23 (56.1 %) |
  Maternal food hypersensitivity | 249 (21.8 %) | 77 (24.4 %) | 6 (40.0 %) | 13 (23.6 %) | 11 (26.8 %) |
  Paternal food hypersensitivity | 135 (11.8 %) | 35 (11.1 %) | 1 (6.7 %) | 7 (12.7 %) | 6 (14.6 %) |
 Urban living environment | 273 (23.9 %) | 99 (31.2 %) | 6 (40.0 %) | 11 (20.0 %) | 8 (19.5 %) |
 Mean number of sibs at home | 1.7 (0.88) | 1.8 (0.99) | 1.4 (0.65) | 1.6 (0.71) | 1.5 (0.64) |
 Female sex | 557 (48.9 %) | 166 (52.4 %) | 6 (40.0 %) | 23 (41.8 %) | 17 (41.5 %) |
 Animals in household at birth | |||||
  Any | 566 (49.6 %) | 164 (50.6 %) | 8 (53.3 %) | 33 (60.0 %) | 26 (63.4 %) |
  Cat | 325 (28.5 %) | 92 (28.4 %) | 4 (26.6 %) | 15 (27.3 %) | 10 (24.4 %) |
  Dog | 204 (17.9 %) | 66 (20.4 %) | 3 (20.0 %) | 15 (27.3 %) | 13 (31.7 %) |
 Season of birth (n = 1139) | |||||
  Summer | 379 (33.3) | 112 (34.6 %) | 2 (13.3 %) | 21 (38.2 %) | 17 (41.5 %) |
  Autumn | 251 (22.0) | 66 (20.4 %) | 7 (46.6 %) | 13 (23.6 %) | 8 (19.5 %) |
  Winter | 183 (16.1) | 51 (15.7) | 2 (13.3 %) | 9 (16.4 %) | 8 (19.5 %) |
  Spring | 326 (28.6) | 95 (29.3 %) | 4 (26.6 %) | 11 (20.0 %) | 8 (19.5 %) |