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Table 1 Demographic, socioeconomic and familial factors of the study participants

From: Incidence and risk factors for food hypersensitivity in UK infants: results from a birth cohort study

  All participants Lost to follow up (2 years) Eligible for DBPCFC
Not challenged Challenged Confirmed food hypersensitivity
n 1140 317 15 55 41
Baseline characteristics
 Caucasian ethnicity 1093 (95.8 %) 304 (96.0 %) 11 (73.3 %) 50 (90.9 %) 39 (95.1 %)
 Smoking during pregnancy 70 (6.1 %) 45 (14.2 %) 0 (0.0 %) 1 (1.8 %) 1 (2.4 %)
 Mothers’ mean age, years 31.9 (5.2) 30.0 (5.8) 31.9 (5.2) 32.0 (5.5) 31.6 (5.3)
 Fathers’ mean age, years 34.1 (5.7) 32.6 (6.4) 33.9 (5.1) 33.9 (4.5) 33.2 (4.6)
 Highest education of parents
  Low (up to 12y) 220 (19.3 %) 86 (27.2 %) 4 (26.7 %) 9 (16.4 %) 7 (17.1 %)
  Intermediate (>12 years, e.g. college) 331 (29.0 %) 96 (30.2 %) 3 (20.0 %) 19 (34.5 %) 13 (31.7 %)
  High (e.g. university) 565 (49.6 %) 121 (38.3 %) 8 (53.3 %) 27 (49.1 %) 21 (51.2 %)
 Allergies in family
  Maternal atopy (A, AR or E) 765 (67.1 %) 210 (66.4 %) 13 (86.7 %) 48 (87.3 %) 36 (87.8 %)
  Paternal atopy (A, AR or E) 610 (53.5 %) 170 (53.7 %) 11 (73.3 %) 30 (54.5 %) 23 (56.1 %)
  Maternal food hypersensitivity 249 (21.8 %) 77 (24.4 %) 6 (40.0 %) 13 (23.6 %) 11 (26.8 %)
  Paternal food hypersensitivity 135 (11.8 %) 35 (11.1 %) 1 (6.7 %) 7 (12.7 %) 6 (14.6 %)
 Urban living environment 273 (23.9 %) 99 (31.2 %) 6 (40.0 %) 11 (20.0 %) 8 (19.5 %)
 Mean number of sibs at home 1.7 (0.88) 1.8 (0.99) 1.4 (0.65) 1.6 (0.71) 1.5 (0.64)
 Female sex 557 (48.9 %) 166 (52.4 %) 6 (40.0 %) 23 (41.8 %) 17 (41.5 %)
 Animals in household at birth
  Any 566 (49.6 %) 164 (50.6 %) 8 (53.3 %) 33 (60.0 %) 26 (63.4 %)
  Cat 325 (28.5 %) 92 (28.4 %) 4 (26.6 %) 15 (27.3 %) 10 (24.4 %)
  Dog 204 (17.9 %) 66 (20.4 %) 3 (20.0 %) 15 (27.3 %) 13 (31.7 %)
 Season of birth (n = 1139)
  Summer 379 (33.3) 112 (34.6 %) 2 (13.3 %) 21 (38.2 %) 17 (41.5 %)
  Autumn 251 (22.0) 66 (20.4 %) 7 (46.6 %) 13 (23.6 %) 8 (19.5 %)
  Winter 183 (16.1) 51 (15.7) 2 (13.3 %) 9 (16.4 %) 8 (19.5 %)
  Spring 326 (28.6) 95 (29.3 %) 4 (26.6 %) 11 (20.0 %) 8 (19.5 %)
  1. Figures represent numbers (%) or mean (SD)
  2. A asthma, AR allergic rhinitis, E eczema