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Immediate anaphylaxis after the ingestion of fig fruit (Ficus carica)

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Rationale

Ficus carica is a species of flowering plant in the genus Ficus, from the family Moraceae, known as the common fig. Allergic anaphylactic reactions to fig fruit are scarcely reported.

Methods

A 50 year-old female experienced an episode of respiratory nasal and ocular symptoms (rhinoconjuntivitis) and severe abdominal pain immediately after the ingestion of a fig fruit. No bronchial symptoms were associated.

Results

Diagnostic work-up showed a positive prick-prick with both fresh raw and dried fig fruit with a total serum IgE of 312 UI/L and a significant serum specific IgE to fig fruit. Co-sensitization to rubber latex and tropical fruits and cross-reactivity between Ficus benjamina latex, was also studied and a distinctive serum molecular allergy diagnostic profile (ISAC®) was obtained. The patient did not consent to undergo a double blind placebo controlled challenge to fig fruit.

Conclusion

Herein we present the case of an IgE-mediated allergic anaphylactic reaction to fig fruit showing no cross-reactivity to rubber latex allergens.

Consent

Written informed consent was obtained from the patient for publication of this abstract and any accompanying images. A copy of the written consent is available for review by the Editor of this journal.

Author information

Correspondence to Ruperto Gonzalez Perez.

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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Keywords

  • Ocular Symptom
  • Double Blind Placebo
  • Severe Abdominal Pain
  • Tropical Fruit
  • Rubber Latex