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  • Open Access

Immediate anaphylaxis after the ingestion of fig fruit (Ficus carica)

  • Ruperto Gonzalez Perez1,
  • Paloma Poza Guedes1,
  • Inmaculada Sanchez Machin1 and
  • Victor Matheu Delgado1
Clinical and Translational Allergy20155(Suppl 3):P167

Published: 30 March 2015


Ocular SymptomDouble Blind PlaceboSevere Abdominal PainTropical FruitRubber Latex


Ficus carica is a species of flowering plant in the genus Ficus, from the family Moraceae, known as the common fig. Allergic anaphylactic reactions to fig fruit are scarcely reported.


A 50 year-old female experienced an episode of respiratory nasal and ocular symptoms (rhinoconjuntivitis) and severe abdominal pain immediately after the ingestion of a fig fruit. No bronchial symptoms were associated.


Diagnostic work-up showed a positive prick-prick with both fresh raw and dried fig fruit with a total serum IgE of 312 UI/L and a significant serum specific IgE to fig fruit. Co-sensitization to rubber latex and tropical fruits and cross-reactivity between Ficus benjamina latex, was also studied and a distinctive serum molecular allergy diagnostic profile (ISAC®) was obtained. The patient did not consent to undergo a double blind placebo controlled challenge to fig fruit.


Herein we present the case of an IgE-mediated allergic anaphylactic reaction to fig fruit showing no cross-reactivity to rubber latex allergens.


Written informed consent was obtained from the patient for publication of this abstract and any accompanying images. A copy of the written consent is available for review by the Editor of this journal.

Authors’ Affiliations

Allergy Department, Hospital Del Torax, Santa Cruz De Tenerife, Spain


© Gonzalez Perez et al; licensee BioMed Central Ltd. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.