Skip to content

Advertisement

  • Invited speaker presentation
  • Open Access

Introductory lecture: Pollen food allergy syndrome

  • Riccardo Asero1
Clinical and Translational Allergy20111(Suppl 1):S35

https://doi.org/10.1186/2045-7022-1-S1-S35

Published: 12 August 2011

Keywords

Food AllergyFood AllergenClinical ExpressionPollen AllergenBirch Pollen

The term pollen-food allergy syndrome (PFAS) defines a series of clinical symptoms appearing shortly after the ingestion of plant-derived foods in subjects with pollen allergy. The patients with PFAS are primarily allergic to pollen and subsequently react to food allergens as a consequence of the homology between pollen and plant-food proteins. The two highly conserved proteins responsible for the large majority of cases of pollen-food allergy syndrome are the pathogenesis-related proteins group 10 (PR-10), including the major birch pollen allergen Bet v 1 and homologous proteins in different fruits and vegetables, and profilin, a plant pan-allergen present in cell structure of all the vegetable kingdom. Although it has been generally thought that the clinical expression of the pollen food-allergy syndrome is uniquely the so-called “oral allergy syndrome”, recent reports suggest that the ingestion of particular foods may be associated with systemic symptoms as well. Recombinant PR-10 proteins and recombinant profilins from different sources are presently available for diagnostic purposes. The presentation will review the available data about the clinical expression, diagnosis, and therapy of the pollen-food allergy syndrome.

Authors’ Affiliations

(1)
Ambulatorio di Allergologia, Clinica San Carlom Paderno, Dugnano, Italy

Copyright

© Asero; licensee BioMed Central Ltd. 2011

This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Advertisement