Skip to main content

Table 3 Drug provocation test results in patients from Group A (Good tolerance to cefadroxil) and Group B (Cross-reactivity with cefadroxil)

From: Penicillin and cephalosporin cross-reactivity: role of side chain and synthetic cefadroxil epitopes

Pat Group Drug Reaction IDR (min) TCD (mg)
1 A AX Urticaria 160 500
PV/CX/CO Good tolerance
2 B PV/CO Good tolerance
3 A PV/CX/CO Good tolerance
4 B PV/CO Good tolerance
5 A AX Anaphylaxis 15 50
PV/CX/CO Good tolerance
6 B PV/CO Good tolerance
7 B PV/CO Good tolerance
8 B PV Anaphylaxis 45 150
CO Good tolerance
9 A PV/CX/CO Good tolerance
10 A PV/CX/CO Good tolerance
11 A PV/CX/CO Good tolerance
12 B PV/CO Good tolerance
13 A PV/CX/CO Good tolerance
14 A PV/CX/CO Good tolerance
15 A PV/CX/CO Good tolerance
16 B PV/CO Good tolerance
17 A PV/CX/CO Good tolerance
18 A PV/CX/CO Good tolerance
19 A AX Urticaria 140 500
PV/CX/CO Good tolerance
20 B PV/CO Good tolerance
21 B PV/CO Good tolerance
22 A CX/CO Good tolerance
23 B CO Good tolerance
24 A PV/CX/CO Good tolerance
25 B PV/CO Good tolerance
26 A AX Generalized pruritus and erythema 60 150
PV/CX/CO Good tolerance
27 A PV/CO Good tolerance
28 A PV/CX/CO Good tolerance
29 A PV/CX/CO Good tolerance
30 A PV/CX/CO Good tolerance
31 B PV/CO Good tolerance
32 B PV/CO Good tolerance
33 A PV/CX/CO Good tolerance
34 B PV Good tolerance
CO Urticaria 25 50
35 B CO Good tolerance
36 A PV/CX/CO Good tolerance
37 B PV/CO Good tolerance
CX Urticaria 50 150
38 B PV/CO Good tolerance
39 B PV/CX/CO Good tolerance
40 A PV/CX/CO Good tolerance -
41 A PV/CX/CO Good tolerance -
42 A PV/CX/CO Good tolerance
43 A PV/CX/CO Good tolerance
44 A PV/CX/CO Good tolerance
45 A PV/CX/CO Good tolerance
46 A PV/CX/CO Good tolerance
47 A CX/CO Good tolerance
48 A CX/CO Good tolerance
49 A PV/CX/CO Good tolerance
50 A PV/CX/CO Good tolerance
51 A PV/CX/CO Good tolerance
52 A PV/CX/CO Good tolerance
53 B PV/CO Good tolerance
CX Anaphylaxis 30 50
54 A PV/CX/CO Good tolerance
  1. Time Interval and Total cumulative dose drug administration and the development of symptoms
  2. Pat, Patients; AX, Amoxicillin; PV, Penicillin V; CX, Cefadroxil; CO, Cefuroxime; IDR (min), Interval between drug administration and development of symptoms in minutes; TCD, Total cumulative dose in mg
\