Skip to main content

Table 3 Drug provocation test results in patients from Group A (Good tolerance to cefadroxil) and Group B (Cross-reactivity with cefadroxil)

From: Penicillin and cephalosporin cross-reactivity: role of side chain and synthetic cefadroxil epitopes

Pat

Group

Drug

Reaction

IDR (min)

TCD (mg)

1

A

AX

Urticaria

160

500

PV/CX/CO

Good tolerance

2

B

PV/CO

Good tolerance

3

A

PV/CX/CO

Good tolerance

4

B

PV/CO

Good tolerance

5

A

AX

Anaphylaxis

15

50

PV/CX/CO

Good tolerance

6

B

PV/CO

Good tolerance

7

B

PV/CO

Good tolerance

8

B

PV

Anaphylaxis

45

150

CO

Good tolerance

9

A

PV/CX/CO

Good tolerance

10

A

PV/CX/CO

Good tolerance

11

A

PV/CX/CO

Good tolerance

12

B

PV/CO

Good tolerance

13

A

PV/CX/CO

Good tolerance

14

A

PV/CX/CO

Good tolerance

15

A

PV/CX/CO

Good tolerance

16

B

PV/CO

Good tolerance

17

A

PV/CX/CO

Good tolerance

18

A

PV/CX/CO

Good tolerance

19

A

AX

Urticaria

140

500

PV/CX/CO

Good tolerance

20

B

PV/CO

Good tolerance

21

B

PV/CO

Good tolerance

22

A

CX/CO

Good tolerance

23

B

CO

Good tolerance

24

A

PV/CX/CO

Good tolerance

25

B

PV/CO

Good tolerance

26

A

AX

Generalized pruritus and erythema

60

150

PV/CX/CO

Good tolerance

27

A

PV/CO

Good tolerance

28

A

PV/CX/CO

Good tolerance

29

A

PV/CX/CO

Good tolerance

30

A

PV/CX/CO

Good tolerance

31

B

PV/CO

Good tolerance

32

B

PV/CO

Good tolerance

33

A

PV/CX/CO

Good tolerance

34

B

PV

Good tolerance

CO

Urticaria

25

50

35

B

CO

Good tolerance

36

A

PV/CX/CO

Good tolerance

37

B

PV/CO

Good tolerance

CX

Urticaria

50

150

38

B

PV/CO

Good tolerance

39

B

PV/CX/CO

Good tolerance

40

A

PV/CX/CO

Good tolerance

-

41

A

PV/CX/CO

Good tolerance

-

42

A

PV/CX/CO

Good tolerance

43

A

PV/CX/CO

Good tolerance

44

A

PV/CX/CO

Good tolerance

45

A

PV/CX/CO

Good tolerance

46

A

PV/CX/CO

Good tolerance

47

A

CX/CO

Good tolerance

48

A

CX/CO

Good tolerance

49

A

PV/CX/CO

Good tolerance

50

A

PV/CX/CO

Good tolerance

51

A

PV/CX/CO

Good tolerance

52

A

PV/CX/CO

Good tolerance

53

B

PV/CO

Good tolerance

CX

Anaphylaxis

30

50

54

A

PV/CX/CO

Good tolerance

  1. Time Interval and Total cumulative dose drug administration and the development of symptoms
  2. Pat, Patients; AX, Amoxicillin; PV, Penicillin V; CX, Cefadroxil; CO, Cefuroxime; IDR (min), Interval between drug administration and development of symptoms in minutes; TCD, Total cumulative dose in mg