Nrf2-interacting nutrients and COVID-19: time for research to develop adaptation strategies

Table 3 Mechanisms involved in the antioxidant effects of Nrf2-interacting nutrients

	Nrf2	mTOR	PPARγ	NFκB	ERK	eIF2α
Effect	Activation	Inhibition	Activation	Inhibition	Activation	Inhibition
Berberine	[173]	[176]	[212]	[71]	[176]	[87]
Curcumin	[180, 213]	[213, 214]	[213]	[213]	[213]	[88]
EGCG	[180]	[214]	[215]	[216, 217]	[217]	[90]
Genistein	[180]	[218]	[219]	[220] [221]	[222]	[91]
Lactobacillus	[223]	[224]	[225]	[223]	[226]
Quercetin	[180]	[227]	[219]	[228]	[229]	[92]
Resveratrol	[180]	[214, 230]	[219]	[220]	[109]	[93]
Sulforaphane	[180]	[98, 231]	[208]	[208]	[232]	[233]

EGCG: Epigallocatechin gallate
The search strategy used in Table 2 was applied in an attempt to assess whether a mechanism of action could be identified

ISSN: 2045-7022