Fig. 1From: The safety and tolerability profile of bilastine for chronic urticaria in children(reproduced with permission from 19)Brain histamine H1 receptor occupancies of various antihistamines and classification for sedating actions. The occupancy data are represented as the mean ± SD of measurements in positron emission tomography after oral single-dose, eye drop (*), or intravenous (i.v.) administration of the drugs; the data were obtained by more than one research group. When H1 receptor occupancy was 20% or lower, the drug could be classified as “non-sedating”Back to article page