Cofactors of wheat-dependent exercise-induced anaphylaxis do not increase highly individual gliadin absorption in healthy volunteers

Table 2 Gliadin concentrations in serum at baseline and at the peak (pg/ml) after each intervention

Proband	Basal gliadin level	Gluten		Gluten + PPI		Gluten + ASA		Gluten + alcohol		Gluten + aerobic exercise		Gluten + anaerobic exercise		Mean (P) (n = 6)³
Proband	(pg/ml)	(pg/ml)¹	(min)²	(pg/ml)¹	(min)²	(pg/ml)¹	(min)²	(pg/ml)¹	(min)²	(pg/ml)¹	(min)²	(pg/ml)¹	(min)²	(pg/ml)¹
P1	15	1161	30	1538	60	664	30	568	60	754	45	767	120	909^ACD
P2	57	1535	90	1559	90	1686	120	1153	120	1184	45	1019	30	1356^CD
P3	306	1318	15	1289	30	1511	15	1237	60	1522	120	1727	120	1434^D
P4	141	2084	15	737	90	855	30	1130	15	971	45	1491	60	1211^CD
P5	306	1137	15	898	30	574	30	738	15	755	30	762	90	811^ABC
P6	121	777	30	384	90	452	30	669	15	569	45	583	30	572^AB
P7	90	549	60	622	15	139	60	234	90	382	15	594	15	420^A
P8	26	425	30	625	60	560	15	298	15	469	15	1113	30	582^AB
P9	184	715	90	857	60	694	120	722	60	942	30	1729	90	943^ABCD
P10	250	946	30	1183	90	1029	60	1366	30	1177	15	844	15	1091^BCD
P11	160	957	30	1091	60	1038	120	1319	30	1252	90	1359	120	1169^CD
P12	186	565	60	1374	30	1257	60	1117	120	1468	90	1767	15	1258^CD
Median	151	952		995		775		928		957		1066
Mean (I)⁴	154	1014^A		1013^A		872^A		879^A		954^A		1146^A
SEM	26	137		111		130		113		109		131

Values in italics designate the highest peak gliadin concentration for each proband
ASA acetyl salicylic acid, PPI proton pump inhibitor, SEM standard error of the mean
¹Peak gliadin concentration; ²time when peak gliadin concentration is reached; ³mean (P) designates the mean peak gliadin concentration of all six interventions per proband displayed per row. Different superscript capital letters indicate significant differences between means (P) of probands (two-way ANOVA, Tukey’s test, p < 0.001); ⁴mean (I) designates the mean peak gliadin concentration of all twelve probands per intervention displayed per column. There were no significant differences between means (I) (two-way ANOVA, Tukey’s test, p = 0.208), which is why all values are marked with the same superscript capital letter

ISSN: 2045-7022