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Table 2 IgG and IgA antibody concentrations (mg/L) in the included study groups. Comparisons of non-atopic asthmatics (NAA) with non-atopic controls (NAC) and atopic asthmatics (AA)

From: Characterization of a subgroup of non-type 2 asthma with cow’s milk hypersensitivity in young subjects

  NAA (n = 24) NAC (n = 24) AA (n = 29) p value NAA-NAC p value NAA-AA
IgG α-LA 1.11 (0.724, 1.72) 1.46 (0.942, 2.27) 3.87 (2.26, 6.63) 0.379 0.001
IgG β-LG 2.43 (1.42, 4.14) 2.50 (1.38, 4.52) 7.31 (4.24, 12.6) 0.975 0.017
IgG casein 7.07 (5.07, 9.86) 10.3 (7.24, 14.7) 9.97 (7.43, 13.3) 0.085 0.078
IgG4 α-LA 0.200 (0.086, 0.461) 0.123 (0.047, 0.318) 0.975 (0.405, 2.34) 0.968 0.002
IgG4 β-LG 0.805 (0.330, 1.96) 0.499 (0.186, 1.33) 2.77 (1.47, 5.22) 0.529 0.052
IgG4 casein 1.20 (0.698, 2.08) 1.18 (0.669, 2.09) 1.55 (0.974, 2.48) 0.826 0.497
IgA α-LA 0.520 (0.479, 0.565) 0.500 (0.500, 0.500) 0.522 (0.477, 0.570) 0.327 0.936
IgA β-LG 0.520 (0.479, 0.564) 0.540 (0.483, 0.603) 0.566 (0.500, 0.641) 0.531 0.234
IgA casein 0.819 (0.581, 1.15) 1.37 (0.978, 1.94) 0.921 (0.681, 1.24) 0.014 0.471
  1. α-LA = α-lactalbumin, β-LG = β-lactoglobulin. Geometric mean (95% CI)