Alpha 1 antitrypsin distribution in an allergic asthmatic population sensitized to house dust mites

Table 4 Relationship between AATD or AAT genotypes and severe persistent asthma

	Severe persistent asthma OR (95%CI)	P value*	Multivariable correction**
PI*MM	1.2700 (0.6–2.69)	0.532	0.382
PI*MS	0.9760 (0.44–2.15)	0.953	0.665
PI*SS	0.00000078 (0–Inf)	0.983	0.992
PI*MZ	0.8910 (0.12–6.92)	0.912	0.953
PI*SZ	0.000000791 (0–Inf)	0.989	0.995
SAATD	6.3600 (0.57–71.5)	0.134	0.711
AATD	0.5680 (0.17–1.88)	0.355	0.992

PI: protease inhibitor, SAATD (severe alpha 1 antitrypsin deficiency, < 57 mg/dl), AATD (alpha1 antitrypsin deficit, < 100 mg/dl)
* Binary logistic regression
** Adjusted for age, conjunctivitis, polyposis, ex-smokers, passive smokers

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