Table 3 Intratonsillar cytokine and transcription factor expression in hypertrophic tonsils and recurrent tonsillitis
From: Tonsillar cytokine expression between patients with tonsillar hypertrophy and recurrent tonsillitis
Cytokine or transcription factor | Tonsillar hypertrophy n = 47 | Recurrent tonsillitis n = 42 |
|---|---|---|
Median (IQR) | Median (IQR) | |
T-helper1 | ||
IFN-γ | 58 (37, 90) | 76 (32, 117) |
Tbet | 54 (31, 83) | 34 (22, 60) |
T-helper2 | ||
IL-13 | 1.2 (0.03, 3.7) | 0.45 (0.02, 2.2) |
GATA3 | 27 (16, 36) | 18 (12, 39) |
T-helper17 | ||
IL-17 | 10 (5.6, 19) | 7.3 (4.1, 13) |
RORC2 | 15 (7.2, 31) | 20 (10, 28) |
T-regulatory | ||
IL-10 | 49 (24, 74) | 35 (21, 64) |
IL-37 | 0.26 (0.15, 0.37) | 0.14 (0.10, 0.24) |
FOXP3 | 46 (20, 87) | 48 (24, 80) |
TGF-β | 163 (105, 232) | 171 (120, 225) |
Type I/III interferons | ||
IFN-α | 15 (0.59, 62) | 9.7 (0.27, 56) |
IFN-β | 24 (2.7, 101) | 22 (2.1, 103) |
IL-28 | 31 (3.1, 88) | 12 (1.4, 75) |
IL-29 | 11 (2.3, 34) | 3.7 (1.3, 26) |