Having concomitant asthma phenotypes is common and independently relates to poor lung function in NHANES 2007–2012

Table 4 Regression models with significant associations between having multiple asthma phenotypes and asthma-related outcomes, adjusted for co-variates

	≥ 2 controller medications		FEV₁ < LLN
	aOR	95% CI	aOR	95% CI
Multiple versus single phenotype	2.03	1.16–3.57	3.21	1.74–5.94
Female gender	1.39	0.77–2.50	1.51	0.81–2.81
Age ≥ 40 yrs	3.01	1.52–5.95	2.55	1.29–5.03
Caucasian versus others	1.38	0.86–2.23	1.37	0.78–2.42
Current smoker versus non-/ex-smokers	1.02	0.52–2.02	2.01	1.21–3.33
Rhinitis	1.08	0.57–2.16	0.94	0.54–1.63
Goodness-of-fit test
χ² (p value)	0.86 (0.56)		0.80 (0.61)

Multivariate logistic regression models adjusted for gender, age, race, current smoking and rhinitis. The aOR values with p < 0.05 are presented in italic
FEV₁ forced expiratory volume in 1 s, LLN lower limit of normal, CI confidence interval, aOR adjusted odds ratio, χ² Chi square goodness-of-fit

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