Fig. 2
From: The kinase LRRK2 is differently expressed in chronic rhinosinusitis with and without nasal polyps
LRRK2 inhibits NFAT1 nuclear translocation. (a–c; ×400 magnification) LRRK2 expression and distribution in control, CRSsNP and CRSwNP groups; d LRRK2 was significantly overexpressed in the CRSsNP group compared with the control group and CRSwNP group; (e–g; ×400 magnification) NFAT1 localization in control, CRSsNP and CRSwNP groups; blue arrows indicate cells with cytosolic NFAT1 staining, red arrows indicate cells with nuclear NFAT1 staining; the top right corner is an enlargement of immuno-positive cells; h the percentage of cells with NFAT1 nuclear staining was much higher in CRSwNP group compared with the control group and CRSsNP group. **p < 0.01, ****p < 0.0001