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Table 2 Subject lung function and sputum

From: Interleukin-25 and eosinophils progenitor cell mobilization in allergic asthma

  Allergen challenge
EAR (% change in FEV1) − 33.67 ± 2.12#
LAR (% change in FEV1) − 24.47 ± 1.77#
Methacoline PC20 (mg/mL)
 Pre-Ag 7.77 ± 1.88
 24 h post-Ag 2.20 ± 0.51*
Total sputum cells (×106 cells/mL)
 Pre-Ag 3.62 ± 0.64
 24 h Post-Ag 6.59 ± 1.27*
Sputum eosinophils (%)
 Pre-Ag 4.68 ± 1.63
 24 h Post-Ag 12.26 ± 2.68*,#
Blood eosinophils (per 109 WBC)
 Pre-Ag 38 ± 6
 24 h Post-Ag 64 ± 9*
  1. Data are presented as geometric mean ± SEM. There was a significant difference the EAR and LAR % change in FEV1, methacoline PC20, total sputum cells, and sputum and blood eosinophils post-allergen
  2. FEV 1 forced expiratory volume in 1 s; PC20 provocative concentration of methacholine causing a 20% drop in FEV1, Ag allergen, EAR early asthmatic response, LAR late asthmatic response, WBC white blood cells, HPC hemopoietic progenitor cells, EoP eosinophil progenitors
  3. *p < 0.05 comparison to baseline and #p < 0.05 comparison to diluent