Skip to main content

Table 3 Crude effect estimates for the associations between risk factor in early childhood and RC, allergic RC and non-allergic RC at 14 years of age

From: Early childhood risk factors for rhinoconjunctivitis in adolescence: a prospective birth cohort study

  RC Allergic RC Non-allergic RC
Totala Yes/no cOR (CI 95%) Totala Yes/no cOR (CI 95%) Totala Yes/no cOR (CI 95%)
Gender    1.53 (0.99–2.36)    2.33 (1.39–3.91)*    0.65 (0.32–1.33)
 Boys (n = 178)   67/111   165 54/111   124 13/111  
 Girls (n = 194)   55/139   168 29/149   164 25/139  
FH (n = 174) 372 72/102 2.09 (1.35–3.25)* 333 52/102 2.43 (1.46–4.06)* 288 19/102 1.45 (0.73–2.88)
Early sensitization to inhalant allergens (n = 113) 372 47/66 1.75 (1.10–2.77)* 333 37/66 2.24 (1.34–3.76)* 288 10/66 1.00 (0.46–2.16)
Early sensitization to foods (n = 204) 372 80/124 1.94 (1.24–3.03)* 333 56/124 2.11 (1.25–3.55)* 288 24/124 1.74 (0.86–3.52)
s-IgE > 4.00 SU/ml to inhalant allergens (n = 56) 372 31/25 3.07 (1.72–5.48)* 333 28/25 4.58 (2.48–8.47)* 288   
s-IgE > 4.00 SU/ml to food allergens (n = 57) 372 34/23 3.81 (2.12–6.84)* 333 30/23 5.59 (3.01–10.39)* 288   
FA (n = 18) 372 14/4 7.97 (2.57–24.78)* 333 12/4 10.39 (3.25–36.22)* 288 2/4 3.42 (0.60–19.33)
AD (n = 87) 372 48/39 3.51 (2.13–5.78)* 333 41/39 5.28 (3.05–9.15)* 288 7/39 1.22 (0.50–2.97)
Early wheeze (n = 59) 372 23/36 1.38 (0.78–2.45) 333 17/36 1.53 (0.81–2.90) 288 6/36 1.12 (0.44–2.86)
CB IgE 0.3 (n = 62) 301 22/40 1.11 (0.62–2.00) 268 18/40 1.44 (0.76–2.73) 232 3/40 0.41 (0.12–1.43)
ETS (n = 192) 372 47/145 0.45 (0.29–0.71)* 333 34/145 0.50 (0.30–0.83)* 288 13/145 0.38 (0.18–0.77)*
Maternal tobacco smoking in pregnancy (n = 110) 372 30/80 0.69 (0.42–1.13) 333 24/80 0.86 (0.50–1.49)* 288 6/80 0.40 (0.16–0.99)*
Breast feed (n = 247) 362 78/169 0.76 (0.48–1.21) 323 51/169 0.67 (0.40–1.13) 277 26/169 0.99 (0.46–2.11)
Pets (n = 231) 372 75/156 0.96 (0.62–1.50) 333 52/156 1.01 (0.61–1.69) 288 22/156 0.83 (0.41–1.66)
Social class (n = 305) 372 99/206 0.92 (0.53–1.61) 333 64/206 0.72 (0.39–1.32) 288 34/206 1.82 (0.61–5.38)
Overweight at 3 years (n = 25) 320 8/17 0.86 (0.36–2.07) 285 3/17 0.46 (0.13–1.60) 243 5/17 1.87 (0.64–5.45)
Cesarean section (n = 44) 365 18/26 1.53 (0.80–2.92) 327 11/26 1.38 (0.65–2.93) 285 7/26 1.92 (0.77–4.79)
Older siblings (n = 182) 372 51/131 0.65 (0.42–1.01) 333 32/131 0.57 (0.34–0.94)* 288 19/131 0.91 (0.46–1.80)
  1. aTotal number of children with data included in the analysis
  2. P ≤ 0.05