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Table 3 Crude effect estimates for the associations between risk factor in early childhood and RC, allergic RC and non-allergic RC at 14 years of age

From: Early childhood risk factors for rhinoconjunctivitis in adolescence: a prospective birth cohort study

 

RC

Allergic RC

Non-allergic RC

Totala

Yes/no

cOR (CI 95%)

Totala

Yes/no

cOR (CI 95%)

Totala

Yes/no

cOR (CI 95%)

Gender

  

1.53 (0.99–2.36)

  

2.33 (1.39–3.91)*

  

0.65 (0.32–1.33)

 Boys (n = 178)

 

67/111

 

165

54/111

 

124

13/111

 

 Girls (n = 194)

 

55/139

 

168

29/149

 

164

25/139

 

FH (n = 174)

372

72/102

2.09 (1.35–3.25)*

333

52/102

2.43 (1.46–4.06)*

288

19/102

1.45 (0.73–2.88)

Early sensitization to inhalant allergens (n = 113)

372

47/66

1.75 (1.10–2.77)*

333

37/66

2.24 (1.34–3.76)*

288

10/66

1.00 (0.46–2.16)

Early sensitization to foods (n = 204)

372

80/124

1.94 (1.24–3.03)*

333

56/124

2.11 (1.25–3.55)*

288

24/124

1.74 (0.86–3.52)

s-IgE > 4.00 SU/ml to inhalant allergens (n = 56)

372

31/25

3.07 (1.72–5.48)*

333

28/25

4.58 (2.48–8.47)*

288

  

s-IgE > 4.00 SU/ml to food allergens (n = 57)

372

34/23

3.81 (2.12–6.84)*

333

30/23

5.59 (3.01–10.39)*

288

  

FA (n = 18)

372

14/4

7.97 (2.57–24.78)*

333

12/4

10.39 (3.25–36.22)*

288

2/4

3.42 (0.60–19.33)

AD (n = 87)

372

48/39

3.51 (2.13–5.78)*

333

41/39

5.28 (3.05–9.15)*

288

7/39

1.22 (0.50–2.97)

Early wheeze (n = 59)

372

23/36

1.38 (0.78–2.45)

333

17/36

1.53 (0.81–2.90)

288

6/36

1.12 (0.44–2.86)

CB IgE 0.3 (n = 62)

301

22/40

1.11 (0.62–2.00)

268

18/40

1.44 (0.76–2.73)

232

3/40

0.41 (0.12–1.43)

ETS (n = 192)

372

47/145

0.45 (0.29–0.71)*

333

34/145

0.50 (0.30–0.83)*

288

13/145

0.38 (0.18–0.77)*

Maternal tobacco smoking in pregnancy (n = 110)

372

30/80

0.69 (0.42–1.13)

333

24/80

0.86 (0.50–1.49)*

288

6/80

0.40 (0.16–0.99)*

Breast feed (n = 247)

362

78/169

0.76 (0.48–1.21)

323

51/169

0.67 (0.40–1.13)

277

26/169

0.99 (0.46–2.11)

Pets (n = 231)

372

75/156

0.96 (0.62–1.50)

333

52/156

1.01 (0.61–1.69)

288

22/156

0.83 (0.41–1.66)

Social class (n = 305)

372

99/206

0.92 (0.53–1.61)

333

64/206

0.72 (0.39–1.32)

288

34/206

1.82 (0.61–5.38)

Overweight at 3 years (n = 25)

320

8/17

0.86 (0.36–2.07)

285

3/17

0.46 (0.13–1.60)

243

5/17

1.87 (0.64–5.45)

Cesarean section (n = 44)

365

18/26

1.53 (0.80–2.92)

327

11/26

1.38 (0.65–2.93)

285

7/26

1.92 (0.77–4.79)

Older siblings (n = 182)

372

51/131

0.65 (0.42–1.01)

333

32/131

0.57 (0.34–0.94)*

288

19/131

0.91 (0.46–1.80)

  1. aTotal number of children with data included in the analysis
  2. * P ≤ 0.05
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Clinical and Translational Allergy

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