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Table 2 Skin test concentrations for perioperative agents

From: Approach to the diagnosis of drug hypersensitivity reactions: similarities and differences between Europe and North America

  ENDA proposal American proposal
SPT (mg/mL) IDT (mg/mL) SPT (mg/mL) IDT (mg/mL)
Thiopental 25 2.5   0.2
Propofol 10 1 10–1 10–0.1
Ketamine 10 1 10 0.25
Etomidate 2 0.2 2 0.2–0.002
Midazolam 5 0.5 5 0.5–0.25
Fentanyl 0.05 0.005 0.05 0.005–0.000005
Alfentanil 0.5 0.05   
Sufentanil 0.005 0.0005   
Remifentanil 0.05 0.005   
Morphine 1 0.01   
Atracurium 1 0.01 10 0.01
Cis-atracurium 2 0.02 2 0.01–0.001
Mivacurium 0.2 0.002   
Rocuronium 10 0.05 10 0.01–0.001
Vecuronium 4 0.4 10 0.1–0.001
Pancuronium 2 0.2 2 0.02
Suxamethonium 10 0.1   
Chlorhexidine 5 0.002 1.2 0.00048
Alcuronium     0.005
Methohexital     0.1
Metocurine     0.002
Succinylcholine    20 0.02–0.05
Thioamyl     0.1
Tubocuranine     0.0003–0.0001
  1. ENDA European Network for Drug Allergy, SPTs skin prick tests, IDTs Intradermal tests
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