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Table 2 Basophil allergen threshold sensitivity (CD-sens) and half-maximal effective concentration (EC50)

From: Exploratory analysis of CD63 and CD203c expression in basophils from hazelnut sensitized and allergic individuals

Subject group

No. of subjects

CD63

CD203c

EC50 (ng/ml)

CD-sens

p values

EC50 (ng/ml)

CD-sens

p values

Sensitized

20

15.18 (1.73–1336)

6.59 (0.07–57.84)

 

10.09 (1.21–33.38)

10.03 (3.55–82.90)

 

OAS

20

2.24 (1.05–7.12)

44.73 (14.07–96.38)

0.028

0.97 (0.17–6.95)

104.55 (14.92–602.48)

0.006

Systemic

12

2.61 (0.98–9.94)

40.40 (10.23–104.61)

NS

1.74 (0.55–7.95)

59.35 (13.27–190.12)

NS

Symptomatic (OAS + systemic)

32

2.24 (1.04–7.70)

44.73 (13.01–96.72)

0.018

1.27 (0.37–7.02)

80.33 (14.64–267.87)

0.009

  1. Values are given as median with interquartile range (IQR). Statistical significances were analyzed with Mann–Whitney U test compared to the sensitized group