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Table 2 Basophil allergen threshold sensitivity (CD-sens) and half-maximal effective concentration (EC50)

From: Exploratory analysis of CD63 and CD203c expression in basophils from hazelnut sensitized and allergic individuals

Subject group No. of subjects CD63 CD203c
EC50 (ng/ml) CD-sens p values EC50 (ng/ml) CD-sens p values
Sensitized 20 15.18 (1.73–1336) 6.59 (0.07–57.84)   10.09 (1.21–33.38) 10.03 (3.55–82.90)  
OAS 20 2.24 (1.05–7.12) 44.73 (14.07–96.38) 0.028 0.97 (0.17–6.95) 104.55 (14.92–602.48) 0.006
Systemic 12 2.61 (0.98–9.94) 40.40 (10.23–104.61) NS 1.74 (0.55–7.95) 59.35 (13.27–190.12) NS
Symptomatic (OAS + systemic) 32 2.24 (1.04–7.70) 44.73 (13.01–96.72) 0.018 1.27 (0.37–7.02) 80.33 (14.64–267.87) 0.009
  1. Values are given as median with interquartile range (IQR). Statistical significances were analyzed with Mann–Whitney U test compared to the sensitized group