Atopic dermatitis prevention in children following maternal probiotic supplementation does not appear to be mediated by breast milk TSLP or TGF-β

Table 1 Baseline characteristics of participating families and allergy related disease in the children at 2 years

Allergy related disease at 2 years	n	n (%)	n	n (%)	p-value^c
Atopic dermatitis, n (%)	129	29 (22.5)	130	45 (34.6)	0.031
Asthma, n (%)	129	7 (5.4)	130	12 (9.2)	0.240
Allergic rhinoconjunctivits, n (%)	125	1 (0.8)	129	0 (0.0)	0.492
Sensitisation^d, n (%)	122	19 (15.6)	124	15 (12.1)	0.429

^aMaternal smoking reported during pregnancy, 6 weeks or 12 months postpartum; ^bCompliance with the study protocol was defined by consumption of the study milk on at least 50 % of days from 36 weeks gestation to 12 postpartum, no consumption of other products with probiotics and at least partial breastfeeding until 3 months postpartum; ^c p-value calculated using χ²-test, except for allergic rhinoconjunctivits where a Fisher’s exact p value is reported; ^d Allergic sensitisation defined as positive skin prick test (wheal ≥ 3 mm) and or positive sIgE (≥ 0.35 kUL⁻¹)

ISSN: 2045-7022