Cow’s milk allergy in Dutch children: an epigenetic pilot survey

Table 2 Top 5 differential methylated positions (DMPs) in combined, girls and boys analysis

Probe	p	Adj. p	Delta	Gene	Region
Combined
cg07687119	6.4E−06	0.942	0.009	HOXC4/5/6	5UTR/body/body
cg01599189	1.1E−05	0.942	0.020	NBPF1	5′UTR
cg09789536	2.8E−05	0.942	0.020	KLHL17	Body
cg11433629	2.9E−05	0.942	−0.012	IGR	NA
cg23339709	2.9E−05	0.942	0.009	OR8U8/OR5M8	Body/exon1
Girls
cg23876832^a	1.7E−07	0.081	0.214	IGR	NA
cg13181291	1.8E−06	0.427	−0.016	GABPB2	Body
cg13700939	1.3E−05	0.999	0.065	IGR	NA
cg09573389	1.3E−05	0.999	0.039	C10orf58	TSS1500
cg24691332	3.0E−05	0.999	0.024	PARD3	Body
Boys
cg06644124	1.6E−06	0.773	0.034	ZNF281	1stExon/5UTR
cg11126313	1.2E−05	0.997	0.009	CCR3	5UTR
cg09357684	1.4E−05	0.997	0.064	THAP3	TSS1500
cg09175834	1.5E−05	0.997	0.018	NAV3	1stExon
cg21255128	2.1E−05	0.997	0.018	C7orf50	Body

p p value, adj. p adjusted p value (BH), Delta expressed as β difference, IGR inter genic region, 5′-UTR 5′ untranslated region, Body genebody, TSS1500 transcription start site 1500 bp upstream
^aHigh frequency (CEU MAF > 0.05) SNP located at position 34 of probe. Adjusted p values <0.05 were assumed significant

ISSN: 2045-7022