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Table 3 Nasal provocation test response thresholds

From: Allergy immunotherapy with a hypoallergenic recombinant birch pollen allergen rBet v 1-FV in a randomized controlled trial

A
rBet v 1-FV Threshold response after treatment in 1st year
  BU/mL 555 1,666 5,000 15,000 45,000 150,000 negative
Threshold response at baseline 555 3 3 0 0 0 0 1
1,666 1 2 1 2 0 0 0
5,000 0 1 0 1 0 0 0
15,000 0 0 0 0 0 0 0
45,000 0 0 0 0 0 0 0
rBet v 1-FV Threshold response after treatment in 2nd year
  BU/mL 555 1,666 5,000 15,000 45,000 150,000 negative
Threshold response at baseline 555 0 4 0 2 0 0 0
1,666 0 0 2 0 1 1 0
5,000 0 0 1 0 0 1 0
15,000 0 0 0 0 0 0 0
45,000 0 0 0 0 0 0 0
B
Comparator Threshold response after treatment in 1st year
  BU/mL 555 1,666 5,000 15,000 45,000 150,000 negative
Threshold response at baseline 555 0 0 2 0 0 0 0
1,666 2 2 3 1 0 0 0
5,000 0 1 0 0 2 0 0
15,000 0 0 0 0 0 0 0
45,000 0 0 0 1 0 0 0
Comparator Threshold response after treatment in 2nd year
  BU/mL 555 1,666 5,000 15,000 45,000 150,000 negative
Threshold response at baseline 555 1 0 0 0 0 0 0
1,666 1 1 4 0 0 0 0
5,000 0 0 1 0 1 0 1
15,000 0 0 0 0 0 0 0
45,000 0 0 0 1 0 0 0
  1. Data indicate numbers of subjects and their responses at baseline compared with that after 1 year or 2 years of treatment with (A) rBet v 1-FV or (B) comparator
  2. Bold printed numbers represent no change in response, and data to the right or the left an increase or decrease in tolerance respectively