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Table 3 Nasal provocation test response thresholds

From: Allergy immunotherapy with a hypoallergenic recombinant birch pollen allergen rBet v 1-FV in a randomized controlled trial

A

rBet v 1-FV

Threshold response after treatment in 1st year

 

BU/mL

555

1,666

5,000

15,000

45,000

150,000

negative

Threshold response at baseline

555

3

3

0

0

0

0

1

1,666

1

2

1

2

0

0

0

5,000

0

1

0

1

0

0

0

15,000

0

0

0

0

0

0

0

45,000

0

0

0

0

0

0

0

rBet v 1-FV

Threshold response after treatment in 2nd year

 

BU/mL

555

1,666

5,000

15,000

45,000

150,000

negative

Threshold response at baseline

555

0

4

0

2

0

0

0

1,666

0

0

2

0

1

1

0

5,000

0

0

1

0

0

1

0

15,000

0

0

0

0

0

0

0

45,000

0

0

0

0

0

0

0

B

Comparator

Threshold response after treatment in 1st year

 

BU/mL

555

1,666

5,000

15,000

45,000

150,000

negative

Threshold response at baseline

555

0

0

2

0

0

0

0

1,666

2

2

3

1

0

0

0

5,000

0

1

0

0

2

0

0

15,000

0

0

0

0

0

0

0

45,000

0

0

0

1

0

0

0

Comparator

Threshold response after treatment in 2nd year

 

BU/mL

555

1,666

5,000

15,000

45,000

150,000

negative

Threshold response at baseline

555

1

0

0

0

0

0

0

1,666

1

1

4

0

0

0

0

5,000

0

0

1

0

1

0

1

15,000

0

0

0

0

0

0

0

45,000

0

0

0

1

0

0

0

  1. Data indicate numbers of subjects and their responses at baseline compared with that after 1 year or 2 years of treatment with (A) rBet v 1-FV or (B) comparator
  2. Bold printed numbers represent no change in response, and data to the right or the left an increase or decrease in tolerance respectively