Anaphylaxis after systemic challenge with Ara h 1, 2, 3, or 6. C3H/HeOuJ mice were intragastrically exposed to PBS, (control) or PE and CT during a 4 week period, as described in material and methods. On day 35, mice received a systemic i.p. challenge with PE or Ara h 1, 2, 3, or 6, directly followed by measurement of rectal temperature at indicated time points after challenge. Upper panel shows the PE sensitized mice, lower panel shows the not sensitized control mice. Data are represented as mean ± SEM of 8 mice. *: p < 0.05 or **: p < 0.01 compared to control. #: p < 0.05 compared to PE challenged mice.