Table 3 Agreement and variability in classification of DBPCFC outcome
From: Standardized food challenges are subject to variability in interpretation of clinical symptoms
All DBPCFC (n =191) | DBPCFC with symptoms (n =111) | |||||
|---|---|---|---|---|---|---|
1 | 2 | 3 | 1 | 2 | 3 | |
Agreement with initial DBPCFC outcome | 79% | 82% | 87% | 65% | 69% | 78% |
1:2 | 1:3 | 2:3 | 1:2 | 1:3 | 2:3 | |
Inter-observer agreement | 78% | 76% | 76% | 76% | 61% | 60% |
κ (95% CI) | 0.65 (0.56-0.74) | 0.59 (0.50-0.68) | 0.59 (0.50-0.68) | 0.46 (0.39-0.53) | 0.35 (0.22-0.48) | 0.31 (0.25-0.38) |
Overall agreement | 69% | 50% | ||||
1 | 2 | 3 | 1 | 2 | 3 | |
Intra-observer agreement* | 77% | 83% | 88% | 67% | 70% | 81% |
κ (95% CI) | 0.63 (0.45-0.82) | 0.71 (0.54-0.89) | 0.77 (0.62-0.92) | 0.50 (0.37-0.63) | 0.52 (0.39-0.65) | 0.60 (0.45-0.60) |