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Table 1 Challenge data and patients characteristics

From: Patterns of suspected wheat-related allergy: a retrospective single-centre case note review in 156 patients

Group 1 Oral wheat allergy
Patient no. Age (y) Sex Atopic diseases Symptoms at challenge Other food allergies Threshold (g) Outgrown
1 0.7 M AD, AB U, E Rye 0.75 Ch + An
2 0.7 M AD, AB U, D, V   20.0 An
3 0.7 M AD U Egg, Milk, Rye 8.84 Ch + An
4 0.8 M AD, AB U, A, C, E, P Cashew, Egg, Pistacio 15.75 An
5 0.8 F AD, AR, AB U, V Egg 7.75 Ch + An
6 0.9 M AD, AB U Egg 25.0 Ch + An
7 0.9 M AD, AR U, R, C, V Egg, Milk, Rye 7.75 Ch + An
8 1.4 M AD U Egg 25.0 Ch + An
9 1.5 M AD U, AB, V Rye 4.0 No
10 2.1 M AD, AR, AB U, C, D, E, R Egg, Milk 15.75 Ch + An
11 2.5 F AD U, E, OAS Egg, Milk, Poppy seeds 0.25 Ch + An
12 2.7 M AD, AB U Egg, Hazelnut, Peanut 25.0 An
13 3.0 M AD, AR, AB U Egg 7.75 No
14 3.6 M AD, AR, AB U, P Melon, Milk, Rye 8.0 Ch + An
15 5.6 M AD U   25.0 Ch + An
Negative 16-48 Age 0–6, F = 7, M = 26 AD = 27, AR = 5, AB = 5   Egg = 15, Milk =6, Peanut = 6, Hazelnut =3 Soya = 1, Lamb =1, Shrimp = 1, None = 1   
Negative 49-59 Age 7–18, F = 5, M = 6 AD = 6, AR = 7, AB = 7   Egg = 3, Milk = 2, Peanut = 1, None = 8   
60 33.5 F   U, C, R   36.0 No
61 37.6 F AR U, E   3.91 No
62 38.5 M   U, OAS, P Rye 50.0 No
63 41.7 F AR U, OAS, P   50.0 No
64 52.2 F AR OAS, P   50.0 No
65 73.4 F AR U, AB, C, R   6.0 No
Negative 66-95 Age 19–67.4, F = 23, M = 7 AD = 4, AR = 11, AB = 7   Egg = 1, Plaice = 1, Sesame = 1, None = 27   
Group 2 Inhalation wheat allergy
Patient no. Age (y) Sex Atopic diseases Symptoms at challenge Other inhalant allergies Occupation Outgrown
96 23.0 F   R, AB   Baker No
97 25.4 F   R, C Durum, Rye Baker No
98 29.5 F   R   Chef No
99 29.9 M   R, C   Baker No
100 24.0 M AR R, C Rye Baker No
101 25.7 F AD, AR R, AB   Baker No
102^ 37.3 F AR R   Grahpic designer No
103^ 40.2 M   R Rye Pizza baker -
104 41.1 F   R, C   Chef -
105 41.6 M   R, C   Pizza baker No
106 43.5 F AR R, C   Baker No
107* 17.6 F    Spelt Student No
108* 33.8 M    Durum, Rye Baker No
Group 3 Wheat dependent exercise induced anaphylaxis
Patient no. Age (y) Sex Atopic diseases Symptoms at challenge sIgE to ω-5 gliadin (kUI/l) Challenge dose (g) Serum lactate (mM)
109 23.0 M   U 14.9 44.0 11.6
110 27.1 F AD U 11.5 44.0 2.3
111 27.4 F AB U < 0.35 44.0 5.9
112 29.7 F   U, A < 0.35 44.0 2.3
113 32.4 F   U < 0.35 44.0 12.6
114 38.1 F   U 29.4 14.7 3.4
115 41.7 M   U 36.6 44.0 3.1
116 42.2 M   U 11.0 44.0 -
117 51.2 M   U 22.7 44.0 4.8
118 67.2 M   U 8.2 29.3 -
Negative 119-123 Age 7–18.9, F = 2, M = 3 AD = 1, AR = 0, AB = 1   n = 0/5 (0%) mean 49.8 [44.0-73.0] mean 10.0 [7.1-12.9]
Negative 124-156 Age 19–63.0, F = 14, M = 19 AD = 2, AR = 9, AB = 1   n = 20/33 (61%) mean 6.7 [0–46.7] mean 45.4 [14.3-58.7] mean 11.5 [4.0-18.7]
  1. F Female, M Male, AD Atopic Dermatitis, AR Allergic Rhinitis, AB Bronchial Asthma, U Urticaria, E Erythema, D Diarrhoea, V Vomiting, A Angioedema, C Conjunctivitis, P Pruritus, R Rhinitis, AB Asthma, OAS Oral Allergy Syndrome, Ch Challenge verified, An Anamnestically verified.
  2. *Negative wheat inhalation challenge.
  3. ^Overlapped with a negative oral wheat challenge.