Table 1 Characteristics of infants at the time of lung function test and findings of bronchial biopsy
From: Bronchoalveolar lavage in infants with recurrent lower respiratory symptoms
N | 39 |
|---|---|
Age, years, median (range) | 0.88 (0.28–1.94) |
Sex, male | 25 (64%) |
Parental asthma | 26 (41%) |
Parental smoking | 9 (23%) |
Symptoms | |
Age at first symptoms (y) | 0.25 (0–1.33) |
Duration (y) | 0.58 (0.17–1.33) |
Wheeze | 23 (59%) |
Frequent wheeze* | 15 (38%) |
Cough | 26 (67%) |
Mucus | 23 (59%) |
Dyspnea | 5 (13%) |
SPT+ | 15 (38%) |
SPT + &/or eczema | 24 (62%) |
Lung function | |
Abnormal | 30 (77%) |
Abnormal with + ve BDR | 12 (40%) |
sGaw, z-score | -2.4 (-5.2–0.9) |
FRC, z-score | 0.37 (-1.5–1.9) |
Bronchial biopsy findings | |
RBM, μm | 3.8 (2.7–6–0) |
Plasma cells/area | 1.3 (0–13.8) |
Neutrophils/area | 0.07 (0–0.88) |
Mast cells/area | 0.39 (0–1.26) |
Lymphocytes/area | 1.7 (0–16.9) |
Total cells/area | 31.4 (16.9–138.9) |
Dg at infancy | |
Asthma | 34 (87%) |
Structural abnormality | 5 (13%) |
Unspecified | 3 (8%) |