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Table 1 Characteristics of infants at the time of lung function test and findings of bronchial biopsy

From: Bronchoalveolar lavage in infants with recurrent lower respiratory symptoms

N 39
Age, years, median (range) 0.88 (0.28–1.94)
Sex, male 25 (64%)
Parental asthma 26 (41%)
Parental smoking 9 (23%)
Symptoms  
  Age at first symptoms (y) 0.25 (0–1.33)
  Duration (y) 0.58 (0.17–1.33)
  Wheeze 23 (59%)
  Frequent wheeze* 15 (38%)
  Cough 26 (67%)
  Mucus 23 (59%)
  Dyspnea 5 (13%)
SPT+ 15 (38%)
SPT + &/or eczema 24 (62%)
Lung function  
  Abnormal 30 (77%)
  Abnormal with + ve BDR 12 (40%)
  sGaw, z-score -2.4 (-5.2–0.9)
  FRC, z-score 0.37 (-1.5–1.9)
Bronchial biopsy findings  
  RBM, μm 3.8 (2.7–6–0)
  Plasma cells/area 1.3 (0–13.8)
  Neutrophils/area 0.07 (0–0.88)
  Mast cells/area 0.39 (0–1.26)
  Lymphocytes/area 1.7 (0–16.9)
  Total cells/area 31.4 (16.9–138.9)
Dg at infancy  
  Asthma 34 (87%)
  Structural abnormality 5 (13%)
  Unspecified 3 (8%)
  1. Lung function and bronchial biopsy findings are presented as medians (range).
  2. *Frequent wheeze, ≥ 3 times.
  3. SPT, skin prick test; BDR, bronchodilator response (sGaw >30%); sGaw, specific airway conductance; FRC, functional residual capacity; RBM, reticular basement membrane.