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Long term nutritional outcome of children fed an amino-acid formula
© Colson et al; licensee BioMed Central Ltd. 2013
Published: 25 July 2013
Some cases of cow’s milk protein allergy (CMPA) require the use of an amino-acids based formula (AAF), with a with a protein level higher than in standard infant formulas. This study assessed the long term consequences of an AAF-based elimination diet on the clinical and biological outcome of CMPA children.
Retrospective analysis of consecutive (2004-2010) patients diagnosed with CMPA (digestive/cutaneous/respiratory symptoms) in a food allergy reference center (Cohort Arsène,n°DC-2009-955), through a telephone survey (Nov2011–Feb2012). Children were enrolled if having adhered to dietetic recommendations, and fed with ≥500mL/day of AAF (Neocate®) or extensive whey hydrolysate-based formula (eWHF, Pepti-Junior®) for ≥6mo, starting either before age 6 months (AAF1, eWHF1)), between ages >6 and 12 months (AAF2) or after age 12 (AAF3).
Age at survey (months) (Mean, SD)
BMI percentile in males at survey: (Mean, SD)
BMI percentile in females at survey (Mean, SD)
Ferritin in males/females (Mean, SD)
Hemoglobin in males/females (Mean, SD)
This study suggests that feeding CMPA children with>500 mL/day of AAF for >15 mo showed a good nutritional outcome with an appropriate anthropomorphic parameters and iron status.
Disclosure of interest
D Colson: Grant/research support from Nutricia Nutrition Clinique, B Michaud: None declared, P Soulaines: None declared, C Dupont: None declared.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.