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Table 4 Demographic and clinical features of patients with positive first COX-2 inhibitor challenge

From: Tolerance to alternative cyclooxygenase-2 inhibitors in nonsteroidal anti-inflammatory drug hypersensitive patients

Variable Patients (n = 19)
Sex (male/female) n (%) 4/15 (21/79%)
Age (years) (mean ± SD) 53.2 ± 10.9
Reaction to 1 NSAID n (%) 12 (63%)
Reaction to various NSAIDs n (%) 7 (37%)
Reaction to paracetamol1 4 (21%)
Co-morbid disorders n (%)  
- Chronic spontaneous urticaria 3 (16%)
- Asthma 4 (21%)
Diagnosed non-selective NSAID hypersensitivity n (%)  
- Patient history; repeated reaction to the same culprit drug 11 (58%)
- Patient history; no/unknown repeated reaction to the same culprit drug 3 (15%)
- Oral challenge with the culprit drug 5 (26%)
  1. 1By patient history.