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Table 1

From: Angiotensin converting enzyme-gene polymorphisms in normal subjects, atopic individuals and those with anaphylaxis to venom, food and drugs

ACE genotype

D D

I D

I I

Healthy Controls

Atopics

Anaphylaxis

Cutaneous & RS

Mean Serum ACE Levels U/L±SEM

Serum ACE V's Healthy Controls

Healthy controls (HC) N=119 (%)

53 (45%)

44 (37%)

22 (18%)

 

P=0.142

P=0.009

P=0.053

48.9±6.2

 

Atopic controls N=49 (%)

15 (31%)

26 (53%)

8 (16%)

P=0.142

 

P=0.425

P=0.025

47.9±3.5

P=0.866

Anaphylaxis N=118 (%)

30 (25%)

58 (50%)

30 (25%)

P=0.009

P=0.425

  

33.2±3.0

P=0.012

Cutaneous & Respiratory anaphylaxis

15 (56%)

12 (44%)

0 (0%)

P=0.053

P=0.025

    

Airway angioedema ± CVS collapse

13* (14%)

46 (52%)

30 (34%)

P<0.001

P=0.024

 

P<0.001

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