ACE genotype | D D | I D | I I | Healthy Controls | Atopics | Anaphylaxis | Cutaneous & RS | Mean Serum ACE Levels U/L±SEM | Serum ACE V's Healthy Controls |
---|---|---|---|---|---|---|---|---|---|
Healthy controls (HC) N=119 (%) | 53 (45%) | 44 (37%) | 22 (18%) |  | P=0.142 | P=0.009 | P=0.053 | 48.9±6.2 |  |
Atopic controls N=49 (%) | 15 (31%) | 26 (53%) | 8 (16%) | P=0.142 |  | P=0.425 | P=0.025 | 47.9±3.5 | P=0.866 |
Anaphylaxis N=118 (%) | 30 (25%) | 58 (50%) | 30 (25%) | P=0.009 | P=0.425 |  |  | 33.2±3.0 | P=0.012 |
Cutaneous & Respiratory anaphylaxis | 15 (56%) | 12 (44%) | 0 (0%) | P=0.053 | P=0.025 | Â | Â | Â | Â |
Airway angioedema ± CVS collapse | 13* (14%) | 46 (52%) | 30 (34%) | P<0.001 | P=0.024 |  | P<0.001 |  |  |