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Table 3 Analysis of effect modifiers related to the allergic sensitization of the patients by ordered logistic regression with pollen and the period and the effect modifier(s).

From: Difference in symptom severity between early and late grass pollen season in patients with seasonal allergic rhinitis

Effect modifier

Factors for analysis

2007

 

2008

 
  

Proportional

Odds Ratio (95% CI)

P-value

Proportional

Odds Ratio (95%CI)

P-value

-

Perioda

0.40 (0.32-0.50)

< 0.001

0.49 (0.40-0.60)

< 0.001

Birch sensitization

Perioda

0.32 (0.21-0.48)

< 0.001

0.53 (0.36-0.77)

< 0.001

 

Birch+b

0.71 (0.31-1.59)

0.40

1.26 (0.64-2.48)

0.51

 

Birch+*period

1.40 (0.83-2.38)

0.20

0.91 (0.56-1.44)

0.68

Birch sensitization and pollen season

Perioda

NDd

 

0.52 (0.36-0.76)

< 0.001

 

Birch+ b

ND

 

1.22 (0.61-2.43)

0.58

 

Birchseasonc

ND

 

0.92 (0.58-1.49)

0.76

Birch sensitization and pollen season

Perioda

NDd

 

0.54 (0.43-0.68)

< 0.001

 

Birch+b

ND

 

0.97 (0.59-1.58)

0.90

 

Birchseasonc

ND

 

0.89 (0.65-1.23)

0.49

 

Birch+*Birchseason

ND

 

1.48 (0.94-2.33)

0.09

HDM

Perioda

0.38 (0.29-0.50)

< 0.001

0.52 (0.41-0.66)

< 0.001

 

HDMe

0.73 (0.27-1.93)

0.52

1.25 (0.55-2.84)

0.59

 

HDM * period

1.27 (0.78-2.08)

0.34

0.68 (0.39-1.18)

0.17

  1. The proportional odd ratio, the 95% confidence interval (CI) and the p values for the period and the effect modifier for each model are shown for 2007 and 2008.
  2. a The period refers to the late (index) versus the early season (reference) of the grass pollen season.
  3. bBirch+ refers to patients that are co-sensitized to birch pollen (index) versus patients with a negative skin prick test for birch pollen (reference).
  4. cBirchseason refers to the birch pollen season (index) versus the period outside the birch pollen season (reference).
  5. dND = not determined since in 2007 the birch pollen season was over by the time the symptoms collection started.
  6. eHDM refers to patients with a clinically relevant house dust mite allergy (index) versus patients without an house dust mite allergy (reference).