Fig. 2
From: Reduced expression of miR-146a in human bronchial epithelial cells alters neutrophil migration
The expression of miR-146a-influenced chemokines is increased in brush biopsy airway epithelial cells from asthma patients with neutrophilic asthma phenotype. Relative mRNA expression of indicated miR-146a-influenced genes (a), genes associated with Th2 type responses (b) and interferon dependent genes (c) in bronchial brushing specimens from patients with asthma was measured by RT-qPCR and compared to the expression levels in the samples from control individuals. a–c Patients were categorized into inflammatory phenotypes based on BALF cell percentages: eosinophilic (E), > 2% of eosinophils and < 3% of neutrophils in BALF; neutrophilic (N), < 2% eosinophils and > 3% neutrophils in BALF; paucigranulocytic (P), < 2% of eosinophils and < 3% neutrophils in BALF). Data represent mean ± SEM. One-way ANOVA, *P < 0.05, **P < 0.01