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Table 2 Select comorbid conditions at baseline and follow-up

From: Elderly versus younger patients with hereditary angioedema type I/II: patient characteristics and safety analysis from the Icatibant Outcome Survey

Comorbid conditions, n (%)

Baseline

Follow-up

Elderly (≥ 65 years)

Younger (< 65 years)

P

Elderly (≥ 65 years)

Younger (< 65 years)

P

Bleeding

4 (4.0)

5 (0.6)

0.0130

4 (4.0)

5 (0.6)

0.0130

Cardiovascular/cerebrovascular

50 (50)

69 (8.9)

 < 0.0001

26 (26.0)

49 (6.3)

<0.0001

Diabetes

11 (11.0)

17 (2.2)

0.0001

6 (6.0)

8 (1.0)

0.0027

Gastrointestinal

11 (11.0)

19 (2.5)

0.0002

7 (7.0)

24 (3.1)

0.0757

Hepatic

1 (1.0)

0 (0.0)

0.1147

2 (2.0)

1 (0.1)

0.0362

Immunological

2 (2.0)

25 (3.2)

0.7592

2 (2.0)

36 (4.7)

0.3008

Infections

1 (1.0)

8 (1.0)

1.0000

4 (4.0)

25 (3.2)

0.5650

Neoplasia

3 (3.0)

6 (0.08)

0.0735

0 (0.0)

2 (0.3)

1.0000

Neurological

1 (1.0)

9 (1.2)

1.0000

3 (3.0)

9 (1.2)

0.1498

Osteoarticular

1 (1.0)

7 (0.9)

1.0000

2 (2.0)

17 (2.2)

1.0000

Psychiatric

7 (7.0)

23 (3.0)

0.0706

6 (6.0)

25 (3.2)

0.1549

Pulmonary

7 (7.0)

11 (1.4)

0.0023

2 (2.0)

10 (1.3)

0.6380

Renal/urogenital

4 (4.0)

5 (0.6)

0.0130

3 (3.0)

6 (0.8)

0.0735