Abstracts from the 8th Drug Hypersensitivity Meeting (DHM)

Table 1 Distributions of drugs classification related to SJS/TEN and comparison with US FDA label

Anti-epileptic drugs/antipsychotics	US FDA	n	(%)
Carbamazepine	Labeled	268	26.07
Phenytoin	Labeled	137	13.33
Lamotrigine	Labeled	104	10.12
Phenobarbital	Labeled	21	2.04
Oxcarbazepine	Labeled	18	1.75
Valproic acid	Labeled	2	0.19
Bupropion	Labeled	1	0.10
Fluoxetine	Labeled	1	0.10
Levetiracetam	Labeled	1	0.10

Antibiotics/antiviral agents	US FDA	n	(%)
Sulfamethoxazole	Labeled	81	7.88
Aminopenicillins^a	Labeled	30	2.92
Quinolones^b	Labeled	26	2.53
Cephalosporins^c	Labeled	24	2.33
Clarithromycine	Labeled	9	0.88
Sulfadoxine/pyrimethamine	Labeled	6	0.58
Doxycycline	Labeled	5	0.49
Dapsone	Labeled	4	0.39
Piperacillin	Labeled	4	0.39
Rifampicin	Not labeled	4	0.39
Vancomycin	Labeled	4	0.39
Clindamycin	Labeled	2	0.19
Fluconazole	Labeled	2	0.19
Imipenem	Labeled	2	0.19
Metronidazole	Labeled	2	0.19
Nevirapine	Labeled	2	0.19
Tetracycline	Not labeled	1	0.10
Azithromycin	Labeled	1	0.10
Floxacillin	Not approved	1	0.10
Streptomycin	Not labeled	1	0.10
Sulfadiazine	Labeled	1	0.10

NSAIDs	US FDA	n	(%)
Diclofenac potassium	Labeled	9	0.88
Piroxicam	Labeled	8	0.78
Etoricoxib	Not approved	7	0.68
Celecoxib	Labeled	4	0.39
Mefenamic acid	Labeled	4	0.39
Ibuprofen	Labeled	3	0.29
Meloxicam	Labeled	2	0.19
Etodolac	Labeled	1	0.10
Metamizole	Not approved	1	0.10
Naproxen	Labeled	1	0.10

Other drugs	US FDA	n	(%)
Allopurinol	Labeled	202	19.65
Sulfasalazine	Labeled	19	1.85
Esomeprazole	Labeled	8	0.78
Strontium ranelate	Not approved	8	0.78
Acetaminophen	Labeled	1	0.10
Acetylcysteine	Not labeled	1	0.10
Carbocysteine	Not approved	1	0.10
Dimercaptopropane	Not approved	1	0.10
Erlotinib hydrochloride	Labeled	1	0.10
Hydroxychloroquine	Labeled	1	0.10
Omeprazole	Labeled	1	0.10
Pantoprazole	Labeled	1	0.10

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