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Table 2 Skin test concentrations for perioperative agents

From: Approach to the diagnosis of drug hypersensitivity reactions: similarities and differences between Europe and North America

 

ENDA proposal

American proposal

SPT (mg/mL)

IDT (mg/mL)

SPT (mg/mL)

IDT (mg/mL)

Thiopental

25

2.5

 

0.2

Propofol

10

1

10–1

10–0.1

Ketamine

10

1

10

0.25

Etomidate

2

0.2

2

0.2–0.002

Midazolam

5

0.5

5

0.5–0.25

Fentanyl

0.05

0.005

0.05

0.005–0.000005

Alfentanil

0.5

0.05

  

Sufentanil

0.005

0.0005

  

Remifentanil

0.05

0.005

  

Morphine

1

0.01

  

Atracurium

1

0.01

10

0.01

Cis-atracurium

2

0.02

2

0.01–0.001

Mivacurium

0.2

0.002

  

Rocuronium

10

0.05

10

0.01–0.001

Vecuronium

4

0.4

10

0.1–0.001

Pancuronium

2

0.2

2

0.02

Suxamethonium

10

0.1

  

Chlorhexidine

5

0.002

1.2

0.00048

Alcuronium

   

0.005

Methohexital

   

0.1

Metocurine

   

0.002

Succinylcholine

  

20

0.02–0.05

Thioamyl

   

0.1

Tubocuranine

   

0.0003–0.0001

  1. ENDA European Network for Drug Allergy, SPTs skin prick tests, IDTs Intradermal tests