Table 3 Diagnostic accuracy of the basophil activation test to peanut using different gating strategies
Gating strategy | ||
|---|---|---|
CD123+ HLADR− | CD203c+ CD123+ HLADR− | |
Optimal cut-off | 6.8 | 8.1 |
AUC ROC for the cut-off | 0.91 | 0.97 |
Accuracy (%) | 91 | 97 |
Sensitivity (%) | 88 | 98 |
Specificity (%) | 94 | 96 |
PPV (%) | 93 | 95 |
NPV (%) | 90 | 98 |
%True positives | 40 | 45 |
%False positives | 3 | 2 |
%True negatives | 51 | 52 |
%False negatives | 5 | 1 |
LR+ | 14.7 | 24.4 |
LR− | 0.13 | 0.02 |