Figure 3From: Heterogeneous responses and cross reactivity between the major peanut allergens Ara h 1, 2,3 and 6 in a mouse model for peanut allergy Dendritic cell -T cell responses to peanut proteins ex vivo. Bone marrow derived dendritic cells were pulsed overnight with PE, Ara h 1, 2, 3 or 6. Hereafter, these dendritic cells were incubated for 72 h with splenic CD4+ T cells derived from mice immunized with PE, Ara h 1, 2, 3 or 6. Graphs depict levels of IL-5 and IL-13 after stimulation. Shown is a representative of 3 experiments and data are represented as mean ± SEM of quadruplicates. *: p < 0.05, **: p < 0.01 or ***: p < 0.001 compared to medium control.Back to article page