Eczema phenotypes and risk of allergic and respiratory conditions in school age children

Table 1 Characteristics of children and their mothers

	Subjects n = 4277
Maternal characteristics
Age at enrollment, years mean (SD)	31.7 (4.5)
Parity, nulliparous % (n)	59 (2526)
Maternal education, higher % (n)	59 (2510)
History of eczema, allergy and asthma, yes % (n)	61 (2597)
Child characteristics
Sex, female % (n)	51 (2181)
Gestational age at birth, weeks median (2.5–97.5th percentile)^a	40.1 (35.5–42.3)
Birth weight, grams mean (SD)^a	3443.1 (566.9)
Ethnicity, non-European % (n)	24 (1006)
Breastfeeding, ever % (n)	93 (3961)
Eczema, ever % (n)^a	23 (859)
Eczema phenotypes % (n)
Never	76 (3229)
Early transient	9 (363)
Mid-transient	6 (259)
Late transient	8 (333)
Persistent	2 (93)
Current asthma, yes % (n)^b	5 (203)
Inhalant sensitization, yes % (n)^b	32 (985)
Food sensitization, yes % (n)^b	7 (209)
Physician diagnosed inhalant allergy, yes % (n)^b	12 (447)
Allergic rhinitis, yes % (n)^a	20.6 (734)
Physician diagnosed food allergy, yes % (n)^b	2 (79)
Lung function, Z-scores mean (SD)^a
FVC	0.18 (0.91)
FEV₁	0.13 (0.96)
FEV₁/FVC	− 0.12 (0.95)
FEF₇₅	− 0.00 (0.91)

Values are percentages (absolute values), mean (SD) or median (2.5–97.5th percentile) after imputation. ^aData was missing and not imputed for gestational age at birth (0.2%), birth weight (0.1%), ever eczema (11.6%), allergic rhinitis (26.9%), and lung function (11.5%). ^bData on the following outcomes were not imputed for the individual analysis and were missing for: current asthma (9.7%), inhalant (26.9%) and food sensitization (27.1%), physician diagnosed inhalant (10.9%) and food allergy (12.7%). They were imputed for the combined outcome analysis and values are for current asthma (yes) 6% (n = 237), inhalant sensitization (yes) 33% (n = 1394), food sensitization (yes) 8% (n = 336), physician-diagnosed inhalant allergy (yes) 12% (n = 521) and physician-diagnosed food allergy (yes) 3% (n = 105)

ISSN: 2045-7022