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Fig. 6 | Clinical and Translational Allergy

Fig. 6

From: A novel ELISA method to determine human MrgX2 in chronic urticaria

Fig. 6

Clinical application of human MrgX2-ELISA. a Healthy subjects frequency distribution of human blood MrgX2 concentration in the population (n = 75). b ROC curve of human MrgX2 protein expression (n = 150), green line represents the diagnostic reference line; blue line represents the ROC curve of MrgX2. c Scatter plot of blood MrgX2 concentration in CU patients (n = 75) and healthy subjects (n = 75). d Histogram of blood MrgX2 concentration in CU patients (n = 75) and healthy subjects (n = 75). e Comparison of blood MrgX2 concentration in healthy male (n = 31) and healthy famale (n = 44). f Comparison of blood MrgX2 concentration in CU male (n = 31) and CU famale (n = 44). Student’s t test (nonparametric tests) was used to determine statistical significance. Data are expressed as mean ± SEM from at least three independent experiments. ****p < .0001 vs. control group

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