Citrullinated histone H3, a marker of extracellular trap formation, is increased in blood of stable asthma patients

Table 4 Independent determinants of circulating H3cit in asthmatics

	β	95% CI
FEV1/VC, %	− 0.15	− 0.28 to − 0.03
TLC, L	0.41	0.28 to 0.54
Macrophages, number per 1 ml of BAL fluid	0.21	0.07 to 0.34
Neutrophils, number per 1 ml of BAL fluid	0.36	0.24 to 0.50
IL-12(p70) in serum, pg/ml	− 0.18	− 0.32 to − 0.05
hsCRP, mg/l	0.37	0.22 to 0.51
F = 6.65, R² = 0.58, p = 0.0002

The resulting standardized regression coefficient (β) with 95% confidence intervals (95% CI) for a factor (independent variable) indicates the increase/decrease in standard deviations (SDs) of dependent variable, when that particular factor increases with 1 SD and all other variables in the model are unchanged

ISSN: 2045-7022