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Table 4 Independent determinants of circulating H3cit in asthmatics

From: Citrullinated histone H3, a marker of extracellular trap formation, is increased in blood of stable asthma patients

  β 95% CI
FEV1/VC,  % − 0.15 − 0.28 to − 0.03
TLC, L 0.41 0.28 to 0.54
Macrophages, number per 1 ml of BAL fluid 0.21 0.07 to 0.34
Neutrophils, number per 1 ml of BAL fluid 0.36 0.24 to 0.50
IL-12(p70) in serum, pg/ml − 0.18 − 0.32 to − 0.05
hsCRP, mg/l 0.37 0.22 to 0.51
F = 6.65, R2 = 0.58, p = 0.0002
  1. The resulting standardized regression coefficient (β) with 95% confidence intervals (95% CI) for a factor (independent variable) indicates the increase/decrease in standard deviations (SDs) of dependent variable, when that particular factor increases with 1 SD and all other variables in the model are unchanged
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