| Asthma n = 60 | Controls n = 50 | p-value |
---|---|---|---|
Age, years | 50 (39–56) | 45.5 (39–53) | NS |
Female gender | 44 (73.7) | 29 (58.0) | NS |
Height, m | 1.63 (1.58–1.71) | 1.65 (1.6–1.76) | NS |
Body mass index (BMI), kg/m2 | 26.9 (23.4–31.6) | 26.4 (23.0–28.1) | NS |
History of smoking | 18 (30.0) | 17 (34.0) | NS |
Active smokers | 7 (11.7) | 8 (16.0) | NS |
Arterial hypertension | 27 (45.0) | 16 (32.0) | NS |
Diabetes mellitus | 8 (13.3) | 5 (10.0) | NS |
Hypercholesterolemia | 17 (28.3) | 16 (32.0) | NS |
Medications used: | |||
---|---|---|---|
 Inhaled corticosteroids | 59 (98.3) |  |  |
 Long-acting β2-agonists | 49 (81.7) |  |  |
 Montelukast | 9 (15.0) |  |  |
 Oral corticosteroids | 17 (28.3) |  |  |
Atopy | 41 (68.3) | Â | Â |
Asthma duration, years | 10 (5–15) |  |  |
Asthma control (according to Asthma Control Test results) | |||
---|---|---|---|
 Well-controlled (score > 19) | 15 (25.0) |  |  |
 very poorly controlled (score > 16) | 25 (41.7) |  |  |
Asthma severity (GINA): | |||
---|---|---|---|
 Mild | 9 (15.0) |  |  |
 Moderate | 21 (35.0) |  |  |
 Severe | 30 (50.0) |  |  |
Prebronchodilator FEV1/VC, % | 67.8 (59.4–75.9) |  |  |
Postbronchodilator FEV1/VC, % | 73.1 (68.2–79.7) |  |  |
Postbronchodilator TLC, L [% of predicted value] | 5.76 (5.18–6.47) [111.8 (103.3–119.8)] |  |  |
Postbronchodilator RV, L [% of predicted value] | 2.23 (1.67–2.66) [123.6 (108.3–147.2)] |  |  |