Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper

Table 9 Summary of the evidence for ‘efficacy of systemic steroids in sinonasal disease + concomitant asthma

Study	LOE (1a to 5)	Study design	Study groups	Clinical endpoints efficacy	Conclusion
Ikeda et al. [99]	3	Prospective RCT	Adult CRSwNP and CRSsNP patients undergoing ESS	1. Sinonasal and pulmonary symptoms 2. Systemic GCS need	1. Improvement of FEV₁ 2. No significant changes in systemic GCS need

RCT randomized controlled trial, CRS chronic rhinosinusitis, CRSsNP chronic rhinosinusitis without nasal polyps, CRS chronic rhinosinusitis, CRSwNP chronic rhinosinusitis with nasal polyps, GCS glucocorticosteroids

ISSN: 2045-7022