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Table 3 Cytokine or transcription factor expression

From: Rhinovirus species and tonsillar immune responses

Cytokine or
transcription
factor
RV-A
n = 16
RV-B
n = 12
RV-C
n = 14
P value
univariate
P value
multivariate
Adjustments
Th1 -type
 IFN-γ71*
(27, 104)
58
(34, 72)
72
(33, 98)
0.990.61Spring
 Tbet72
(27, 309)
33
(15, 60)
40
(15, 70)
0.0820.056Respiratory symptoms, spring
Th2 -type
 IL-130.40
(0.018, 5.0)
0.37
(0.020, 3.4)
1.8
(0.36, 7.6)
0.140.14
 GATA331
(13, 50)
20
(6.2, 33)
21
(12, 37)
0.360.98Spring
Th17 -type
 IL-1715
(9.1, 26)
14
(3.8, 26)
8.0
(4.0, 14)
0.370.36Age
 RORC222
(9.7, 71)
18
(7.2, 29)
14
(6.2, 25)
0.310.025Respiratory symptoms
Treg -type
 IL-1055
(32, 84)
40
(14, 62)
33
(22, 74)
0.340.96Age, spring
 IL-370.38
(0.14, 0.50)
0.22**
(0.14, 0.34)
0.27
(0.14, 0.34)
0.640.11Respiratory symptoms
 FOXP356
(19, 107)
33
(13, 89)
29
(16, 88)
0.470.12Rhinitis
 TGF-β146
(94, 185)
192
(108, 252)
139
(102, 187)
0.490.49
Type I/III interferons
 IFN-α5.8
(0, 44)
0.37**
(0.33, 38)
22
(2.9, 78)
0.230.045Respiratory symptoms
 IFN-β15
(3.3, 81)
4.9
(2.2, 68)
61
(7.7, 116)
0.300.30
 IL-2825*
(1.4, 88)
9.7
(1.4, 62)
32
(13, 109)
0.410.41
 IL-295.9
(1.3, 35)
3.1
(1.3, 22)
11
(4.4, 40)
0.530.53
  1. IFN interferon, Tbet T-box transcription factor, IL interleukin, GATA3 GATA-binding factor 3, RORC RAR-related orphan receptor C, FOXP forkhead box protein, TGF tumour growth factor, Th T helper cell, Treg T regulatory cell
  2. Values are arbitrary units × 104 relative to EF1α
  3. Data are expressed as median (interquartile range)
  4. Adjustments are selected backward stepwise from significant differences between groups (sex, rhinitis on the operation day, any respiratory symptoms on the operation day, operation made spring, operation made fall) and age
  5. *n = 15
  6. **n = 11