Table 1 Woolf’s correction
From: Association of IKZF1 SNPs in cold medicine-related Stevens–Johnson syndrome in Thailand
rs number of IKZF1 SNP | Genotypes | Case (N = 57) | Control (N = 171) | Allele 1 vs 2 | Genotype 11 vs 12 + 22 | Genotype 11 + 12 vs 22 | |
|---|---|---|---|---|---|---|---|
p-value Corrected p-value OR (95%CI) | p-value Corrected p-value OR (95%CI) | p-value Corrected p-value OR (95%CI) | |||||
rs897693 | 11 | T/T | 36/57 (63.2%) | 114/171 (66.7%) | 0.69 | 0.63 | 1.00 |
12 | T/C | 17/57 (29.8%) | 45/171 (26.3%) | – | – | – | |
22 | C/C | 4/57 (7%) | 12/171 (7%) | – | – | – | |
rs4917014 | 11 | T/T | 46/57 (80.7%) | 100/171 (58.5%) | 1.22.E−03 | 2.46.E−03 | 0.0619 |
12 | G/T | 11/57 (19.3%) | 61/171 (35.7%) | 4.89.E−03 | 9.86.E−03 | – | |
22 | G/G | 0/57 (0%) | 10/171 (5.8%) | 2.91 (1.49–5.68) | 2.97 (1.44–6.13) | – | |
rs4917129 | 11 | T/T | 47/57 (82.5%) | 109/171 (63.7%) | 2.59.E−03 | 8.48.E−03 | 4.97.E−02 |
12 | T/C | 10/57 (17.5%) | 51/171 (29.8%) | 1.03.E−02 | 3.39.E−02 | 0.199 | |
22 | C/C | 0/57 (0%) | 11/171 (6.4%) | 2.82 (1.40–5.68) | 2.67 (1.26–5.66) | 8.24* (0.48–142.08) | |
rs10276619 | 11 | G/G | 25/57 (43.9%) | 52/171 (30.4%) | 1.21.E−02 | 0.063 | 2.97.E−02 |
12 | G/A | 26/57 (45.6%) | 78/171 (45.6%) | 4.84.E−02 | – | 0.119 | |
22 | A/A | 6/57 (10.5%) | 41/171 (24%) | 1.76 (1.13–2.74) | – | 2.68 (1.07–6.70) | |