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Table 2 Patient characteristics

From: Eliciting dose is associated with tolerance development in peanut and cow’s milk allergic children

Outcome

Peanut allergy

Cow’s milk allergy

Hen’s egg allergy

N1

Allergic

Tolerant

p-value

N1

Allergic

Tolerant

p-value

N1

Allergic

Tolerant

p-value

N (%)

 

34 (72.34)

13 (27.66)

  

36 (45.00)

44 (55.00)

  

19 (34.55)

36 (65.45)

 

EDa [mg/protein] (median, IQR)

 

228.23 [5.22;535.63)

577.97 [402.23;577.97]

0.010

 

88.38 [5.25;439.25]

1746.50 [84;2187.50]

0.001

 

89.18 [3.51;438.88]

886.54 [206.05;2184.78]

0.038

Follow-up in months (median, IQR)

 

50.50 [38;77]

43.00 [27;72]

  

45.00 [26;74]

23.00 [15;38]

  

67.00 [28;77]

37.00 [25;53]

 

Agea in months (median, IQR)

 

74.50 [51;124]

71.00 [46;98]

0.839

 

33.50 [14;65]

19.50 [12;38]

0.057

 

49.00 [22;57]

39.00 [15;58]

0.352

Sex (%), male

 

20 (58.82)

7 (53.84)

0.758

 

25 (69.44)

25 (56.82)

0.248

 

11 (57.89)

28 (77.78)

0.128

Asthmaa (%)

(33;13)

25 (75.76)

6 (46.15)

0.060

 

17 (47.22)

14 (31.82)

0.162

(18;35)

9 (50.00)

13 (37.14)

0.370

Eczemaa

 

32 (94.12)

12 (92.31)

0.821

 

31 (86.11)

39 (88.64)

0.734

(19;35)

18 (94.74)

33 (94.28)

0.945

Rhinitisa

 

22 (64.71)

3 (23.08)

0.016

(36;42)

6 (16.67)

9 (21.43)

0.596

(18;35)

6 (33.33)

5 (15.63)

0.155

Number of diagnosed allergies to any foods (median, IQR)°

 

1 [1;2]

2 [1;2]

0.516

 

1 [1;2]

1 [1;2]

0.254

 

2 [1;3]

2 [1;2]

0.485

Reaction severitya (median, IQR)

 

4 [2;5]

3 [3;4]

0.886

 

4 [2;6]

4 [1;6]

0.596

 

4 [3;7]

3 [2;4]

0.020

Reaction severity before diagnosis (median, IQR)

 

1 [0;6]

3 [0;6]

0.850

 

7 [4;9]

7 [4;9]

0.303

 

6 [2;7]

2 (0;7]

0.086

sIgEa [kU/L] (median, IQR)

(29;12)

10.70 [2.58;45.90]

1.36 [.31;3.84]

0.080

(17;18)

21.65 [8.57;56.70]

2.80 [.30;6.61]

0.001

(17;18)

12.30 [2.51;32.20]

6.11 [1.07;10.30]

0.063

  1. 1N = Number of patients (allergic;tolerant); Continuous variables are presented by medians and IQRs (Inter quartile range)
  2. aMeasured/diagnosed at initial DBPCFC