|
AAAAI-2011
|
ASCIA-1997
|
BSACI (SCIT)-2011
|
BSACI (VIT)-2011
|
CMICA-2011
|
DSA-2005
|
EAACI (SCIT)-2015
|
EAACI (SLIT)-2015
|
EAACI (VIT)-2015
|
FSACI-2011
|
German-speaking-2014
|
IFIACI (SCIT)-2014
|
IFIACI (VIT)-2014
|
JSA-2017
|
NSAI-2011
|
PTA (SLIT)-2016
|
SEIAC-2011
|
SFA-2003
|
SFFA-2009
|
WHO-1998
|
---|
Lack of communication
|
A
| | |
A
| |
A
|
R
|
R
|
R
|
A
|
A
|
A
|
A
| |
R
|
A
| |
A
|
A
|
R
|
Start during pregnancy
|
Ra
|
R
|
R
|
R
|
R
|
R
|
A
|
A
|
A
|
R
|
Aa
|
Ab
|
R
|
A
|
R
|
R
|
R
|
R
|
R
|
R
|
Beta-blockers
|
R
|
A
|
A
|
R
|
R
|
Ac
|
R
|
R
| |
Ac
|
A
|
R
|
R
|
A
|
R
|
A
|
R
|
A
|
R
|
R
|
ACE-inhibitors
|
R
| | |
R
|
R
| | | |
R
| |
Ad
| | | | | | | |
R
| |
Antidepressants
| | | |
R
| | | | | | | | | | | | | | | | |
Children < 5-6 yo
| |
R
|
A
| |
R
| |
Re
|
Re
|
Re
| | |
Ab
|
A
| |
R
| |
R
|
A
|
Rb
|
Rc
|
Elderly > 65 yo
| | | | |
R
| | | | | | | | | | | |
R
| | | |
Cardiovascular diseases
|
R
| |
R
| |
A
|
A
|
R
|
R
| |
Ac
| | | |
R
|
R
|
A
| | |
A
|
R
|
Uncontrolled asthma
|
R
|
R
|
A
|
A
|
A
|
A
|
A
|
A
|
A
|
A
|
Ag
|
A
|
A
|
A
|
R
|
A
|
R
|
A
|
A
|
R
|
Co-existing active diseases
| | |
A
| |
A
|
A
|
R
|
R
|
R
| | |
R
| | |
R
|
A
| | | | |
Immunodeficiency
| | |
R
|
R
|
R
|
A
|
R
|
R
|
R
|
A
|
A
|
A
| | |
R
|
A
|
R
|
A
|
A
|
R
|
Autoimmunity
| |
R
|
R
|
R
|
R
|
A
|
Rf
|
Rf
|
Rf
|
R
|
R
|
A
|
R
|
A
|
R
|
A
|
R
|
A
|
A
|
R
|
Immunosuppressive agents
| | |
R
| | | |
R
|
R
|
R
| |
A
|
A
| | | | | |
A
| | |
Chronic infections
| | | | | |
A
|
R
|
R
|
R
|
A
| | |
R
| | |
A
| | |
A
| |
Malignancy
| |
R
|
R
|
R
|
R
|
A
|
A
|
A
|
R
|
A
|
R
|
A
|
R
|
A
|
R
|
A
| |
A
| | |
Dermatitis
| |
R
| | | |
R
| | | |
R
| | | | |
R
| | | |
R
|
R
|
Temporary conditions
| | | | | | | | | | |
A
|
R
| | | |
R
|
R
| | | |
Inadequate means/training
| |
A
| |
A
| | | | | | | | | | | | | | | | |
Anaphylaxis to AIT
| |
A
| | | | | | | | | | | | | | | | | | |
- Acronyms of the Societies/Academies are explained in the “Abbreviations” section
- A: absolute contraindications or contraindications of major importance
- R: relative contraindications or special precautions/considerations
- aVIT can be initiated during pregnancy in isolated cases of life-threatening insect venom allergy
- bSCIT is contraindicated while SLIT is not
- cNot a contraindication for VIT
- dContraindicated for VIT
- eFor children < 2 yo it consists an absolute contraindication
- fFor autoimmune disorders in active form it consists an absolute contraindication
- gFollowing the German NVL (Nationale VersorgungsLeitlinie) for the definition of partially controlled asthma, it is mentioned that “AIT may be performed in children in case of partially controlled astma—provided they rarely experience asthma symptoms”