Table 4 Categorisation 2: non-high FeNO and non-high blood eosinophils vs. high FeNO and non-high blood eosinophils
Characteristics | Non-high FeNO and non-high blood eosinophils (n = 98) | High FeNO and non-high blood eosinophils (n = 98) | p-value |
|---|---|---|---|
Sex | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) | 1.0000 |
 Male | 41 (41.8) | 41 (41.8) |  |
Age | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) | 1.0000 |
 Mean (SD) | 48.8 (15.3) | 48.6 (15.6) |  |
 Median (IQR) | 53.0 (27.0) | 53.0 (27.0) |  |
Age group | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) | 0.3072 |
 Under 35 | 23 (23.5) | 24 (24.5) |  |
 35–65 | 65 (66.3) | 57 (58.2) |  |
 66–80 | 10 (10.2) | 17 (17.3) |  |
Smoking status | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) | 1.0000 |
 Non-smoker | 53 (54.1) | 53 (54.1) |  |
 Ex-smoker | 8 (8.2) | 8 (8.2) |  |
 Current smoker | 23 (23.5) | 23 (23.5) |  |
BMI | |||
 n (% non-missing) | 96 (98.0) | 94 (95.9) | 0.0063 |
 Mean (SD) | 29.3 (6.2) | 26.9 (5.8) |  |
 Median (IQR) | 27.9 (8.6) | 25.7 (7.6) |  |
FeNO | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) | < 0.0001 |
 Mean (SD) | 17.7 (7.9) | 60.0 (31.8) |  |
 Median (IQR) | 17.0 (10.0) | 50.0 (25.0) |  |
Blood eosinophil count | |||
 n (% non-missing) | 98 (100.0) | 97 (99.0) | < 0.0001 |
 Mean (SD) | 0.2 (0.1) | 0.3 (0.3) |  |
 Median (IQR) | 0.2 (0.1) | 0.3 (0.3) |  |
Active eczema diagnosisa | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) | 1.0000 |
 Yes | 4 (4.1) | 4 (4.1) |  |
Active rhinitis diagnosisa | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) | 0.7492 |
 Yes | 26 (26.5) | 28 (28.6) |  |
Eczema diagnosis | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) | 0.8763 |
 Yes | 29 (29.6) | 30 (30.6) |  |
Rhinitis diagnosis | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) | 0.4546 |
 Yes | 32 (32.7) | 37 (37.8) |  |
IHD diagnosis | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) | 0.7003 |
 Yes | 4 (4.1) | 3 (3.1) |  |
Heart failure diagnosis | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) |  |
 Yes | 0 (0.0) | 0 (0.0) |  |
Hypertension diagnosis | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) | 0.0967 |
 Yes | 29 (29.6) | 19 (19.4) |  |
Diabetes diagnosis | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) | 0.5513 |
 Yes | 7 (7.1) | 5 (5.1) |  |
GERD active diagnosis | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) | 0.6018 |
 Yes | 9 (9.2) | 7 (7.1) |  |
Predicted peak flow | |||
 n (% non-missing) | 55 (56.1) | 71 (72.4) | 0.6615 |
 Mean (SD) | 520.7 (67.4) | 515.9 (68.6) |  |
 Median (IQR) | 490.8 (137.4) | 493.7 (125.0) |  |
ICS/LABA prescriptions per patient | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) | 0.1318 |
 Mean (SD) | 2.6 (3.1) | 3.4 (3.7) |  |
 Median (IQR) | 1.0 (4.0) | 2.0 (5.0) |  |
Mono ICS prescriptions per patient | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) | 0.0295 |
 Mean (SD) | 1.6 (2.8) | 0.9 (1.9) |  |
 Median (IQR) | 0.0 (2.0) | 0.0 (1.0) |  |
Mean daily SABA dosage (µg) | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) | 0.3731 |
 < 100 | 31 (31.6) | 40 (40.8) |  |
 100–200 | 32 (32.7) | 22 (22.4) |  |
 201–400 | 20 (20.4) | 22 (22.4) |  |
 > 400 | 15 (15.3) | 14 (14.3) |  |
ICS adherenceb | |||
 n (% non-missing) | 98 (100.0) | 98 (100.0) | 0.4778 |
 Mean (SD) | 58.1 (43.5) | 65.7 (67.6) |  |
 Median (IQR) | 49.3 (57.5) | 49.3 (54.8) |  |