|
Characteristics
|
CSU (n = 283)
|
NC (n = 111)
|
p value
|
|---|
|
Age (year)
|
42.4 ± 11.7
|
43.9 ± 11.3
|
0.123
|
|
Female (%)
|
184 (65.0)
|
73 (65.8)
|
0.888
|
|
BMI (kg/m2)
|
23.5 ± 3.9
|
23.1 ± 2.8
|
0.864
|
|
Urticaria duration (month)
|
26.1 ± 51.8
|
NA
| |
|
UAS7 (0–42)
|
24.4 ± 10.3
|
NA
| |
|
Angioedema (%)
|
122 (45.7)
|
NA
| |
|
Aspirin intolerance (%)
|
63/148 (25.5)
|
NA
| |
|
ASST positivity (%)
|
81/268 (30.2)
|
NA
| |
|
ANA positivity (%)
|
58/271 (21.4)
|
NA
| |
|
Atopy (%)
|
150/277 (54.2)
|
NA
| |
|
Log[Total IgE (kU/L)]
|
2.09 ± 0.5
|
1.71 ± 0.6
|
< 0.001
|
|
ECP (kU/L)
|
21.7 ± 18.9
|
12.7 ± 9.6
|
< 0.001
|
|
Total cholesterol (mg/dL)
|
194.9 ± 36.8
|
188.4 ± 40.3
|
0.362
|
|
Triglycerides (mg/dL)
|
150.4 ± 98.7
|
104.2 ± 60.0
|
< 0.001
|
|
LDL (mg/dL)
|
111.9 ± 35.0
|
115.9 ± 35.0
|
0.319
|
|
HDL (mg/dL)
|
55.7 ± 14.9
|
70.2 ± 27.0
|
< 0.001
|
|
Complement 3 (mg/dL)
|
110.1 ± 20.8
| | |
|
Complement 4 (mg/dL)
|
26.6 ± 7.9
| | |
- p values were obtained by Chi square test for categorical variables and Mann–Whitney U-test for continuous variables
- CSU chronic spontaneous urticaria, NC healthy normal control, BMI body mass index, NA not assessable, UAS7 urticaria activity score over 7 days, ASST autologous serum skin test, ANA anti-nuclear antibody, ECP eosinophilic cationic protein, LDL low density lipoprotein, HDL high density lipoprotein
