Skip to main content

Table 1 Baseline characteristics of the study subjects

From: Increased platelet activating factor levels in chronic spontaneous urticaria predicts refractoriness to antihistamine treatment: an observational study

Characteristics

CSU (n = 283)

NC (n = 111)

p value

Age (year)

42.4 ± 11.7

43.9 ± 11.3

0.123

Female (%)

184 (65.0)

73 (65.8)

0.888

BMI (kg/m2)

23.5 ± 3.9

23.1 ± 2.8

0.864

Urticaria duration (month)

26.1 ± 51.8

NA

 

UAS7 (0–42)

24.4 ± 10.3

NA

 

Angioedema (%)

122 (45.7)

NA

 

Aspirin intolerance (%)

63/148 (25.5)

NA

 

ASST positivity (%)

81/268 (30.2)

NA

 

ANA positivity (%)

58/271 (21.4)

NA

 

Atopy (%)

150/277 (54.2)

NA

 

Log[Total IgE (kU/L)]

2.09 ± 0.5

1.71 ± 0.6

< 0.001

ECP (kU/L)

21.7 ± 18.9

12.7 ± 9.6

< 0.001

Total cholesterol (mg/dL)

194.9 ± 36.8

188.4 ± 40.3

0.362

Triglycerides (mg/dL)

150.4 ± 98.7

104.2 ± 60.0

< 0.001

LDL (mg/dL)

111.9 ± 35.0

115.9 ± 35.0

0.319

HDL (mg/dL)

55.7 ± 14.9

70.2 ± 27.0

< 0.001

Complement 3 (mg/dL)

110.1 ± 20.8

  

Complement 4 (mg/dL)

26.6 ± 7.9

  
  1. p values were obtained by Chi square test for categorical variables and Mann–Whitney U-test for continuous variables
  2. CSU chronic spontaneous urticaria, NC healthy normal control, BMI body mass index, NA not assessable, UAS7 urticaria activity score over 7 days, ASST autologous serum skin test, ANA anti-nuclear antibody, ECP eosinophilic cationic protein, LDL low density lipoprotein, HDL high density lipoprotein