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Table 1 Baseline characteristics of the study subjects

From: Increased platelet activating factor levels in chronic spontaneous urticaria predicts refractoriness to antihistamine treatment: an observational study

Characteristics CSU (n = 283) NC (n = 111) p value
Age (year) 42.4 ± 11.7 43.9 ± 11.3 0.123
Female (%) 184 (65.0) 73 (65.8) 0.888
BMI (kg/m2) 23.5 ± 3.9 23.1 ± 2.8 0.864
Urticaria duration (month) 26.1 ± 51.8 NA  
UAS7 (0–42) 24.4 ± 10.3 NA  
Angioedema (%) 122 (45.7) NA  
Aspirin intolerance (%) 63/148 (25.5) NA  
ASST positivity (%) 81/268 (30.2) NA  
ANA positivity (%) 58/271 (21.4) NA  
Atopy (%) 150/277 (54.2) NA  
Log[Total IgE (kU/L)] 2.09 ± 0.5 1.71 ± 0.6 < 0.001
ECP (kU/L) 21.7 ± 18.9 12.7 ± 9.6 < 0.001
Total cholesterol (mg/dL) 194.9 ± 36.8 188.4 ± 40.3 0.362
Triglycerides (mg/dL) 150.4 ± 98.7 104.2 ± 60.0 < 0.001
LDL (mg/dL) 111.9 ± 35.0 115.9 ± 35.0 0.319
HDL (mg/dL) 55.7 ± 14.9 70.2 ± 27.0 < 0.001
Complement 3 (mg/dL) 110.1 ± 20.8   
Complement 4 (mg/dL) 26.6 ± 7.9   
  1. p values were obtained by Chi square test for categorical variables and Mann–Whitney U-test for continuous variables
  2. CSU chronic spontaneous urticaria, NC healthy normal control, BMI body mass index, NA not assessable, UAS7 urticaria activity score over 7 days, ASST autologous serum skin test, ANA anti-nuclear antibody, ECP eosinophilic cationic protein, LDL low density lipoprotein, HDL high density lipoprotein