Table 1 Patient demography of included sesame allergic and tolerant patients; allergy was defined by food challenge or an experienced physician
Group 1a (n = 17)a | Group 1b (n = 18)a | Group 2 (n = 13)a | p values | |
|---|---|---|---|---|
Age (median) | 53 (29–85) | 35 (27–51) | 32 (27–58) | 0.001 |
Sex female | 14 (82%) | 10 (56%) | 10 (77%) | 0.1865 |
Food challenge | 8 (47%) | 1 (6%) | 1 (8%) | 0.0034 |
Total IgE (kU/l) | 295 (39 to > 5000) | 4470 (1010 to > 5000) | > 5000 (518 to > 5000) | < 0.0001 |
Symptoms b | ||||
Mild (Müller 0) | 6 (35%) | 6 (33%) | N.A. | 0.9693 |
Moderate (Müller 1 + 2) | 6 (35%) | 6 (33%) | N.A. | |
Severe (Müller 3 + 4) | 5 (29%) | 6 (33%) | N.A. | |
IgE measurements c | ||||
Sesame extract (n; median, range) | 17 (0, 0–0.32 kU/L) | 18 (4.5, 0.5–75 kU/L) | 13 (3.9, 0.4–48 kU/L) | 0.5338 |
Ses i 1 ISAC (n; median, range) | 6 (0 ISU) | 10 (2.9, 0–22.5 ISU) | 3 (0, 0–6 ISU) | 0.4336 |