Skip to main content

Table 1 Patient demography of included sesame allergic and tolerant patients; allergy was defined by food challenge or an experienced physician

From: Sesame oleosins are minor allergens

  Group 1a (n = 17)a Group 1b (n = 18)a Group 2 (n = 13)a p values
Age (median) 53 (29–85) 35 (27–51) 32 (27–58) 0.001
Sex female 14 (82%) 10 (56%) 10 (77%) 0.1865
Food challenge 8 (47%) 1 (6%) 1 (8%) 0.0034
Total IgE (kU/l) 295 (39 to > 5000) 4470 (1010 to > 5000) > 5000 (518 to > 5000) < 0.0001
Symptoms b
Mild (Müller 0) 6 (35%) 6 (33%) N.A. 0.9693
Moderate (Müller 1 + 2) 6 (35%) 6 (33%) N.A.
Severe (Müller 3 + 4) 5 (29%) 6 (33%) N.A.
IgE measurements c
Sesame extract (n; median, range) 17 (0, 0–0.32 kU/L) 18 (4.5, 0.5–75 kU/L) 13 (3.9, 0.4–48 kU/L) 0.5338
Ses i 1 ISAC (n; median, range) 6 (0 ISU) 10 (2.9, 0–22.5 ISU) 3 (0, 0–6 ISU) 0.4336
  1. aG1a sesame allergic patients without detectable sIgE sensitisation, G1b sesame allergic patients with sIgE sensitisation, G2 sesame tolerant patients with sIgE sensitisation
  2. bSymptom distribution of each group is shown in Additional file 3 :Figure S2
  3. cImmunoCAP and ISAC data were compared between group 1b and 2 since group 1a was selected by lacking sIgE sensitisation; CAP > 0.35 kU/L was considered as positive